FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term adenosylhomocysteinase activity ID (Ontology) GO:0004013 (Gene Ontology)
Definition Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.
Comment
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 adenosylhomocysteinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | adenosylhomocysteinase activity
 NOT | enables | adenosylhomocysteinase activity
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  hydrolase activity
   |__hydrolase activity, acting on carbon-sulfur bonds
       |__adenosylhomocysteinase activity  1 rec.
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Is a hydrolase activity, acting on carbon-sulfur bonds
Part of
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Synonyms
  • "adenosylhomocysteine hydrolase activity" RELATED
    "AdoHcyase activity" RELATED
    "S-adenosyl-L-homocysteine hydrolase activity" RELATED
    "S-adenosylhomocysteinase activity" RELATED
    "S-adenosylhomocysteine hydrolase activity" BROAD
    "S-adenosylhomocysteine synthase activity" RELATED
    "SAHase activity" RELATED
Secondary IDs
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EC:3.13.2.1
MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN
Reactome:R-HSA-174401 "AHCY:NAD+ tetramer hydrolyses AdoHcy"
Reactome:R-HSA-5579084 "Defective AHCY does not hydrolyse AdoHcy"
RHEA:21708