FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term L-alanine:2-oxoglutarate transaminase activity ID (Ontology) GO:0004021 (Gene Ontology)
Definition Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
Also Known As"L-alanine:2-oxoglutarate aminotransferase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 L-alanine:2-oxoglutarate transaminase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | L-alanine:2-oxoglutarate transaminase activity
Spanning Tree (Parents/Children)
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  amino acid transaminase activity
   |__L-alanine:oxo-acid transaminase activity
       |__L-alanine:2-oxoglutarate transaminase activity  1 rec.
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Is a L-alanine:oxo-acid transaminase activity
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Synonyms
  • "alanine aminotransferase activity" BROAD
    "alanine transaminase activity" BROAD[ EC:2 ]
    "alanine-alpha-ketoglutarate aminotransferase activity" RELATED[ EC:2 ]
    "alanine-pyruvate aminotransferase activity" RELATED[ EC:2 ]
    "ALT" RELATED[ EC:2 ]
    "beta-alanine aminotransferase" BROAD[ EC:2 ]
    "glutamic acid-pyruvic acid transaminase activity" RELATED[ EC:2 ]
    "glutamic--alanine transaminase activity" RELATED[ EC:2 ]
    "glutamic--pyruvic transaminase activity" RELATED[ EC:2 ]
    "glutamic-pyruvic aminotransferase activity" RELATED[ EC:2 ]
    "GPT" RELATED[ EC:2 ]
    "L-alanine aminotransferase activity" BROAD[ EC:2 ]
    "L-alanine transaminase activity" BROAD[ EC:2 ]
    "L-alanine-alpha-ketoglutarate aminotransferase activity" RELATED[ EC:2 ]
    "L-alanine:2-oxoglutarate aminotransferase activity" EXACT
    "pyruvate transaminase activity" BROAD[ EC:2 ]
    "pyruvate-alanine aminotransferase activity" RELATED[ EC:2 ]
    "pyruvate-glutamate transaminase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.6.1.2
KEGG_REACTION:R00258
MetaCyc:ALANINE-AMINOTRANSFERASE-RXN
Reactome:R-HSA-507749 "PXLP-K341-GPT2 transaminates PYR to form L-Ala"
Reactome:R-HSA-507775 "PXLP-K341-GPT2 transaminates L-Ala to form PYR"
Reactome:R-HSA-70523 "PXLP-K314-GPT transaminates L-Ala to form PYR"
Reactome:R-HSA-70524 "PXLP-K314-GPT transaminates PYR to form L-Ala"
RHEA:19453