FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term alcohol dehydrogenase (NAD+) activity ID (Ontology) GO:0004022 (Gene Ontology)
Definition Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.[ EC:1 ]
Also Known As "aldo-keto reductase (NAD) activity"
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       6
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 alcohol dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)       2      6
     enables | alcohol dehydrogenase (NAD+) activity       --       6
 NOT | enables | alcohol dehydrogenase (NAD+) activity       --       1
Spanning Tree (Parents/Children)
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  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
   |__alcohol dehydrogenase [NAD(P)+] activity
       |__alcohol dehydrogenase (NAD+) activity  15 rec.
           |__3-methylbutanal reductase (NADH) activity
           |__11-cis-retinol dehydrogenase (NAD+) activity
           |__all-trans-retinol dehydrogenase (NAD+) activity 4 rec.
           |__aryl-alcohol dehydrogenase (NAD+) activity
           |__butanol dehydrogenase (NAD+) activity
           |__ethanol dehydrogenase (NAD+) activity
           |__hexadecanol dehydrogenase (NAD+) activity
           |__indole-3-acetaldehyde reductase (NADH) activity
           |__inositol 2-dehydrogenase (NAD+) activity
           |__L-iditol 2-dehydrogenase (NAD+) activity 3 rec.
           |__methanol dehydrogenase (NAD+) activity
           |__octanol dehydrogenase (NAD+) activity 1 rec.
           |__perillyl-alcohol dehydrogenase (NAD+) activity
           |__xanthoxin dehydrogenase (NAD+) activity
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Is a alcohol dehydrogenase [NAD(P)+] activity
Part of
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Synonyms
  • "ADH" RELATED[ EC:1 ]
    "alcohol dehydrogenase activity" BROAD
    "alcohol:NAD+ oxidoreductase" RELATED[ EC:1 ]
    "aldehyde dehydrogenase (NAD) activity" NARROW
    "aldo-keto reductase (NAD) activity" EXACT
    "aliphatic alcohol dehydrogenase" NARROW[ EC:1 ]
    "ethanol dehydrogenase" NARROW[ EC:1 ]
    "NAD-dependent alcohol dehydrogenase" RELATED[ EC:1 ]
    "NAD-specific aromatic alcohol dehydrogenase" RELATED[ EC:1 ]
    "NADH-alcohol dehydrogenase" RELATED[ EC:1 ]
    "NADH-aldehyde dehydrogenase" RELATED[ EC:1 ]
    "primary alcohol dehydrogenase" BROAD[ EC:1 ]
    "yeast alcohol dehydrogenase" NARROW[ EC:1 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:1.1.1.1
MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN
MetaCyc:RXN-12448
Reactome:R-HSA-2162078 "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+"
Reactome:R-HSA-71707 "ethanol + NAD+ => acetaldehyde + NADH + H+"
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