FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term aldose reductase (NADPH) activity ID (Ontology) GO:0004032 (Gene Ontology)
Definition Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.[ EC:1 ]
Also Known As "alditol:NADP+ 1-oxidoreductase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       8
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 aldose reductase (NADPH) activity (all annotations which use CV term, excluding "NOT" statements)       1      8
     enables | aldose reductase (NADPH) activity       --       8
Spanning Tree (Parents/Children)
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 |__alcohol dehydrogenase (NADP+) activity
     |__aldose reductase (NADPH) activity  9 rec.
         |__D-xylose reductase (NADPH) activity
         |__L-arabinose reductase (NADPH) activity
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Is a alcohol dehydrogenase (NADP+) activity
Part of
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Synonyms
  • "aldehyde reductase activity" RELATED[ EC:1 ]
    "alditol:NADP+ 1-oxidoreductase activity" EXACT
    "aldose reductase activity" RELATED[ EC:1 ]
    "polyol dehydrogenase (NADP(+)) activity" RELATED[ EC:1 ]
Secondary IDs
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KEGG_REACTION:R02820
Reactome:R-HSA-196060 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol"
Reactome:R-HSA-5652172 "AKR1B1 reduces Glc to D-sorbitol"
Reactome:R-HSA-9931850 "AKR1B1 reduces galactose to galactitol"
RHEA:12789
RHEA:59924