FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity ID (Ontology) GO:0004043 (Gene Ontology)
Definition Catalysis of the reaction: (S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O = L-2-aminoadipate + NAD(P)H + 2 H+.[ EC:1 ]
Also Known As"L-aminoadipate-semialdehyde dehydrogenase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity (all annotations which use CV term, excluding "NOT" statements)
     enables | L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity
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  oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
   |__aldehyde dehydrogenase [NAD(P)+] activity
       |__L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity  1 rec.
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Is a aldehyde dehydrogenase [NAD(P)+] activity
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Synonyms
  • "2-aminoadipate semialdehyde dehydrogenase activity" RELATED[ EC:1 ]
    "2-aminoadipic semialdehyde dehydrogenase activity" RELATED[ EC:1 ]
    "AAR" RELATED[ EC:1 ]
    "alpha-aminoadipate reductase activity" RELATED[ EC:1 ]
    "alpha-aminoadipate-semialdehyde dehydrogenase activity" RELATED[ EC:1 ]
    "aminoadipate semialdehyde dehydrogenase activity" RELATED[ EC:1 ]
    "aminoadipate-semialdehyde dehydrogenase activity" RELATED[ EC:1 ]
    "L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase" RELATED[ EC:1 ]
    "L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity" RELATED[ EC:1 ]
    "L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity" RELATED[ EC:1 ]
    "L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity" RELATED[ EC:1 ]
    "L-aminoadipate-semialdehyde dehydrogenase activity" EXACT
Secondary IDs
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EC:1.2.1.31
MetaCyc:1.2.1.31-RXN
Reactome:R-HSA-70941 "alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+"
RHEA:12304
RHEA:12308