FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term amidophosphoribosyltransferase activity ID (Ontology) GO:0004044 (Gene Ontology)
Definition Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O.[ EC:2 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 amidophosphoribosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | amidophosphoribosyltransferase activity       --
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  glycosyltransferase activity
   |__pentosyltransferase activity
       |__amidophosphoribosyltransferase activity  3 rec.
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Is a pentosyltransferase activity
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Synonyms
  • "5'-phosphoribosylpyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "5-phosphoribosyl-1-pyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)" RELATED[ EC:2 ]
    "5-phosphororibosyl-1-pyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "glutamine 5-phosphoribosylpyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "glutamine phosphoribosyldiphosphate amidotransferase activity" RELATED[ EC:2 ]
    "glutamine phosphoribosylpyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity" RELATED[ EC:2 ]
    "phosphoribose pyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "phosphoribosyl pyrophosphate amidotransferase activity" RELATED[ EC:2 ]
    "phosphoribosyldiphosphate 5-amidotransferase activity" RELATED[ EC:2 ]
    "phosphoribosylpyrophosphate glutamyl amidotransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.2.14
KEGG_REACTION:R01072
MetaCyc:PRPPAMIDOTRANS-RXN
Reactome:R-HSA-73815 "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate"
RHEA:14905