FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term argininosuccinate lyase activity ID (Ontology) GO:0004056 (Gene Ontology)
Definition Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.[ EC:4 ]
Comment
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 argininosuccinate lyase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | argininosuccinate lyase activity       1
Spanning Tree (Parents/Children)
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  carbon-nitrogen lyase activity
   |__amidine-lyase activity
       |__argininosuccinate lyase activity  1 rec.
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Is a amidine-lyase activity
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Synonyms
  • "2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)" RELATED[ EC:4 ]
    "2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)" RELATED[ EC:4 ]
    "arginine-succinate lyase activity" RELATED[ EC:4 ]
    "argininosuccinic acid lyase activity" RELATED[ EC:4 ]
    "arginosuccinase activity" RELATED[ EC:4 ]
    "N-(L-argininosuccinate) arginine-lyase activity" RELATED[ EC:4 ]
    "omega-N-(L-arginino)succinate arginine-lyase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.3.2.1
MetaCyc:ARGSUCCINLYA-RXN
Reactome:R-HSA-70573 "argininosuccinate <=> fumarate + arginine"
Reactome:R-HSA-9956524 "ASL variants don't synthesize fumarate and arginine"
RHEA:24020