FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term aromatic-L-amino-acid decarboxylase activity ID (Ontology) GO:0004058 (Gene Ontology)
Definition Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.[ EC:4 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 aromatic-L-amino-acid decarboxylase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | aromatic-L-amino-acid decarboxylase activity
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  carbon-carbon lyase activity
   |__carboxy-lyase activity
       |__aromatic-L-amino-acid decarboxylase activity  1 rec.
           |__5-hydroxy-L-tryptophan decarboxylase activity 1 rec.
           |__L-dopa decarboxylase activity 1 rec.
           |__L-tryptophan decarboxylase activity
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Is a carboxy-lyase activity
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Synonyms
  • "5-hydroxytryptophan decarboxylase activity" NARROW[ EC:4 ]
    "aromatic amino acid decarboxylase activity" RELATED[ EC:4 ]
    "aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)" NARROW[ EC:4 ]
    "aromatic-L-amino-acid carboxy-lyase activity" RELATED[ EC:4 ]
    "DOPA decarboxylase activity" NARROW[ EC:4 ]
    "hydroxytryptophan decarboxylase activity" NARROW[ EC:4 ]
    "L-DOPA decarboxylase activity" NARROW[ EC:4 ]
    "tryptophan decarboxylase activity" NARROW[ EC:4 ]
Secondary IDs
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EC:4.1.1.28
MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN
Reactome:R-HSA-209859 "Decarboxylation of 5-hydroxytryptophan forms serotonin"
Reactome:R-HSA-209924 "Dopa is decarboxylated to dopamine"