FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity ID (Ontology) GO:0004081 (Gene Ontology)
Definition Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.[ EC:3 PubMed:4955726 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity       1
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  pyrophosphatase activity
   |__bis(5'-nucleosyl)-tetraphosphatase activity
       |__bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity  1 rec.
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Is a bis(5'-nucleosyl)-tetraphosphatase activity
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Synonyms
  • "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity" RELATED[ EC:3 ]
    "Ap(4)A hydrolase activity" BROAD[ EC:3 ]
    "Ap(4)Aase activity" BROAD[ EC:3 ]
    "Ap4A hydrolase activity" BROAD[ EC:3 ]
    "Ap4Aase activity" BROAD[ EC:3 ]
    "bis(5'-adenosyl)-tetraphosphatase activity" NARROW[ EC:3 ]
    "bis(5'-guanosyl)-tetraphosphatase activity" NARROW[ EC:3 ]
    "diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity" RELATED[ EC:3 ]
    "diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity" RELATED[ EC:3 ]
    "diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase" NARROW
    "diadenosine P1,P4-tetraphosphatase activity" RELATED[ EC:3 ]
    "diadenosinetetraphosphatase (asymmetrical) activity" NARROW[ EC:3 ]
    "diguanosinetetraphosphatase (asymmetrical) activity" NARROW[ EC:3 ]
    "dinucleoside tetraphosphatase activity" RELATED[ EC:3 ]
    "dinucleosidetetraphosphatase (asymmetrical) activity" RELATED[ EC:3 ]
    "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.6.1.17
MetaCyc:3.6.1.17-RXN
Reactome:R-HSA-5696197 "NUDT2 hydrolyses GP4G to GTP, GMP"
RHEA:22484