FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term branched-chain-amino-acid:2-oxoglutarate transaminase activity ID (Ontology) GO:0004084 (Gene Ontology)
Definition Catalysis of the reaction: a branched-chain amino acid (L-leucine, L-isoleucine and L-valine) + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.[ EC:2 ]
Also Known As"branched-chain amino acid aminotransferase activity" ; "branched-chain-amino-acid transaminase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 branched-chain-amino-acid:2-oxoglutarate transaminase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | branched-chain-amino-acid:2-oxoglutarate transaminase activity
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  transaminase activity
   |__amino acid transaminase activity
       |__branched-chain-amino-acid:2-oxoglutarate transaminase activity  1 rec.
           |__L-isoleucine:2-oxoglutarate transaminase activity 1 rec.
           |__L-leucine:2-oxoglutarate transaminase activity 1 rec.
           |__L-valine:2-oxoglutarate transaminase activity 1 rec.
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Is a amino acid transaminase activity
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Synonyms
  • "branched-chain amino acid aminotransferase activity" EXACT
    "branched-chain amino acid-glutamate transaminase activity" RELATED[ EC:2 ]
    "branched-chain aminotransferase activity" RELATED[ EC:2 ]
    "branched-chain-amino-acid transaminase activity" EXACT
    "branched-chain-amino-acid:2-oxoglutarate aminotransferase activity" RELATED[ EC:2 ]
    "glutamate-branched-chain amino acid transaminase activity" RELATED[ EC:2 ]
    "L-branched chain amino acid aminotransferase activity" RELATED[ EC:2 ]
    "transaminase B activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.6.1.42
Reactome:R-HSA-508179 "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2]"
Reactome:R-HSA-508189 "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1]"
Reactome:R-HSA-70723 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]"
Reactome:R-HSA-70724 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]"