FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity ID (Ontology) GO:0004088 (Gene Ontology)
Definition Catalysis of the reaction: hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H+.
Also Known As "carbamoyl phosphate synthase (glutamine-hydrolyzing) activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  ligase activity, forming carbon-nitrogen bonds
   |__carbon-nitrogen ligase activity, with glutamine as amido-N-donor
       |__carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "carbamoyl phosphate synthase (glutamine-hydrolyzing) activity" EXACT
    "carbamoyl phosphate synthetase activity" RELATED[ EC:6 ]
    "carbamoyl-phosphate synthase (glutamine-hydrolysing) activity" RELATED[ EC:6 ]
    "carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity" RELATED[ EC:6 ]
    "carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity" RELATED[ EC:6 ]
    "carbamoylphosphate synthetase II activity" RELATED[ EC:6 ]
    "carbamyl phosphate synthetase (glutamine) activity" RELATED[ EC:6 ]
    "carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity" RELATED[ EC:6 ]
    "CPS activity" RELATED[ EC:6 ]
    "GD-CPSase activity" RELATED[ EC:6 ]
    "glutamine-dependent carbamoyl-phosphate synthase activity" RELATED[ EC:6 ]
    "glutamine-dependent carbamyl phosphate synthetase activity" RELATED[ EC:6 ]
    "hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity" RELATED[ EC:6 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:6.3.5.5
MetaCyc:CARBPSYN-RXN
Reactome:R-HSA-73577 "CAD hexamer transforms L-Gln to CAP"
RHEA:18633