FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term carbonyl reductase (NADPH) activity ID (Ontology) GO:0004090 (Gene Ontology)
Definition Catalysis of the reaction: a secondary alcohol + NADP+ = a ketone + H+ + NADPH.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 carbonyl reductase (NADPH) activity (all annotations which use CV term, excluding "NOT" statements)       1      4
     enables | carbonyl reductase (NADPH) activity       --       4
Spanning Tree (Parents/Children)
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 |__alcohol dehydrogenase (NADP+) activity
     |__carbonyl reductase (NADPH) activity  5 rec.
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Is a alcohol dehydrogenase (NADP+) activity
Part of
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Synonyms
  • "aldehyde reductase 1" RELATED[ EC:1 ]
    "aldehyde reductase I activity" RELATED[ EC:1 ]
    "ALR3" RELATED[ EC:1 ]
    "carbonyl reductase activity" RELATED[ EC:1 ]
    "NADPH-dependent carbonyl reductase activity" RELATED[ EC:1 ]
    "NADPH2-dependent carbonyl reductase activity" RELATED[ EC:1 ]
    "nonspecific NADPH-dependent carbonyl reductase activity" RELATED[ EC:1 ]
    "prostaglandin 9-ketoreductase activity" NARROW[ EC:1 ]
    "secondary-alcohol:NADP+ oxidoreductase activity" RELATED[ EC:1 ]
    "xenobiotic ketone reductase activity" NARROW[ EC:1 ]
Secondary IDs
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EC:1.1.1.184
MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN
Reactome:R-HSA-8937419 "CBR3 reduces DOX to DOXOL"
RHEA:10724
RHEA:12212
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RHEA:62068
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RHEA:62268
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RHEA:63504
RHEA:64416
RHEA:65056
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RHEA:65496
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RHEA:68148
RHEA:70215
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RHEA:74707
RHEA:81575
RHEA:81583
RHEA:81719
RHEA:82231
RHEA:84223
RHEA:85047
RHEA:85103