FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term cytochrome-b5 reductase activity, acting on NAD(P)H ID (Ontology) GO:0004128 (Gene Ontology)
Definition Catalysis of the reaction: 2 Fe(III)-[cytochrome b5] + NAD(P)H = 2 Fe(II)-[cytochrome b5] + NAD(P)+ + H+.
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Genes
 cytochrome-b5 reductase activity, acting on NAD(P)H (all annotations which use CV term, excluding "NOT" statements)       3
     enables | cytochrome-b5 reductase activity, acting on NAD(P)H       3
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  oxidoreductase activity, acting on NAD(P)H
   |__oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
       |__cytochrome-b5 reductase activity, acting on NAD(P)H  3 rec.
           |__cytochrome-b5 reductase activity, acting on NADH
           |__cytochrome-b5 reductase activity, acting on NADPH
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Is a oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
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Reactome:R-HSA-198824 "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme"
Reactome:R-HSA-6806831 "CYB5Rs reduce MetHb to HbA"