FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term diacylglycerol cholinephosphotransferase activity ID (Ontology) GO:0004142 (Gene Ontology)
Definition Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.[ EC:2 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 diacylglycerol cholinephosphotransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | diacylglycerol cholinephosphotransferase activity
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  phosphotransferase activity, for other substituted phosphate groups
   |__CDP-alcohol phosphatidyltransferase activity
       |__diacylglycerol cholinephosphotransferase activity  1 rec.
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Is a CDP-alcohol phosphatidyltransferase activity
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Synonyms
  • "1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity" RELATED[ EC:2 ]
    "1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity" RELATED[ EC:2 ]
    "1-alkyl-2-acetylglycerol cholinephosphotransferase activity" RELATED[ EC:2 ]
    "alkylacylglycerol choline phosphotransferase activity" RELATED[ EC:2 ]
    "alkylacylglycerol cholinephosphotransferase activity" RELATED[ EC:2 ]
    "CDP-choline diglyceride phosphotransferase activity" RELATED[ EC:2 ]
    "CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity" RELATED[ EC:2 ]
    "cholinephosphotransferase activity" RELATED[ EC:2 ]
    "CPT" RELATED[ EC:2 ]
    "cytidine diphosphocholine glyceride transferase activity" RELATED[ EC:2 ]
    "cytidine diphosphorylcholine diglyceride transferase activity" RELATED[ EC:2 ]
    "diacylglycerol choline phosphotransferase activity" RELATED[ EC:2 ]
    "phosphocholine diacylglyceroltransferase activity" RELATED[ EC:2 ]
    "phosphorylcholine--glyceride transferase activity" RELATED[ EC:2 ]
    "sn-1,2-diacylglycerol cholinephosphotransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.7.8.2
MetaCyc:RXN-5781
Reactome:R-HSA-1482961 "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane"
Reactome:R-HSA-1482973 "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane"
RHEA:32939
RHEA:54232
RHEA:54236
RHEA:54240
RHEA:54244
RHEA:54332
RHEA:54336
RHEA:54344