FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term diacylglycerol O-acyltransferase activity ID (Ontology) GO:0004144 (Gene Ontology)
Definition Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.[ EC:2 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 diacylglycerol O-acyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | diacylglycerol O-acyltransferase activity       --
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  acyltransferase activity, transferring groups other than amino-acyl groups
   |__acylglycerol O-acyltransferase activity
       |__diacylglycerol O-acyltransferase activity  5 rec.
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Is a acylglycerol O-acyltransferase activity
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Synonyms
  • "1,2-diacylglycerol acyltransferase activity" RELATED[ EC:2 ]
    "acyl-CoA:1,2-diacylglycerol O-acyltransferase activity" RELATED[ EC:2 ]
    "diacylglycerol acyltransferase activity" RELATED[ EC:2 ]
    "diglyceride acyltransferase activity" RELATED[ EC:2 ]
    "diglyceride O-acyltransferase activity" RELATED[ EC:2 ]
    "palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.3.1.20
MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN
Reactome:R-HSA-1482889 "DAG is acylated to TAG by DGAT1/2"
Reactome:R-HSA-549192 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]"
Reactome:R-HSA-75900 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]"
Reactome:R-HSA-8848580 "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG"
RHEA:10868
RHEA:38163
RHEA:38219
RHEA:38299
RHEA:38307
RHEA:56536