FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term dihydroorotate dehydrogenase activity ID (Ontology) GO:0004152 (Gene Ontology)
Definition Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 dihydroorotate dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | dihydroorotate dehydrogenase activity       1
Spanning Tree (Parents/Children)
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  oxidoreductase activity
   |__oxidoreductase activity, acting on the CH-CH group of donors
       |__dihydroorotate dehydrogenase activity  2 rec.
           |__dihydroorotate dehydrogenase (fumarate) activity
           |__dihydroorotate dehydrogenase (NAD+) activity
           |__dihydroorotate dehydrogenase (NADP+) activity
           |__dihydroorotate dehydrogenase (quinone) activity 2 rec.
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Is a oxidoreductase activity, acting on the CH-CH group of donors
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Synonyms
Secondary IDs
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KEGG_REACTION:R01868
MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN
Reactome:R-HSA-73569 "DHODH:FMN oxidises (S)-DHO to orotate"
RHEA:18073