FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 6,7-dihydropteridine reductase activity ID (Ontology) GO:0004155 (Gene Ontology)
Definition Catalysis of the reaction: NAD(P)+ + 5,6,7,8-tetrahydropteridine = NAD(P)H + H+ + 6,7-dihydropteridine.[ EC:1 ]
Also Known As"dihydropteridine reductase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 6,7-dihydropteridine reductase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 6,7-dihydropteridine reductase activity
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  oxidoreductase activity, acting on the CH-NH group of donors
   |__oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
       |__6,7-dihydropteridine reductase activity  1 rec.
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Is a oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
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Synonyms
  • "5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity" RELATED[ EC:1 ]
    "5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity" RELATED[ EC:1 ]
    "6,7-dihydropteridine:NAD(P)H oxidoreductase activity" RELATED[ EC:1 ]
    "DHPR activity" RELATED[ EC:1 ]
    "dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity" RELATED[ EC:1 ]
    "dihydropteridine reductase (NADH) activity" RELATED[ EC:1 ]
    "dihydropteridine reductase activity" EXACT
    "dihydropteridine reduction" RELATED
    "NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity" RELATED[ EC:1 ]
    "NAD(P)H2:6,7-dihydropteridine oxidoreductase activity" RELATED[ EC:1 ]
    "NADH-dihydropteridine reductase activity" RELATED[ EC:1 ]
    "NADPH-dihydropteridine reductase activity" RELATED[ EC:1 ]
    "NADPH-specific dihydropteridine reductase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.5.1.34
MetaCyc:1.5.1.34-RXN
Reactome:R-HSA-71130 "q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+"
RHEA:17865
RHEA:17869
RHEA:32247
RHEA:32251