FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term diphosphomevalonate decarboxylase activity ID (Ontology) GO:0004163 (Gene Ontology)
Definition Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.[ EC:4 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 diphosphomevalonate decarboxylase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | diphosphomevalonate decarboxylase activity       1
Spanning Tree (Parents/Children)
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  carbon-carbon lyase activity
   |__carboxy-lyase activity
       |__diphosphomevalonate decarboxylase activity  1 rec.
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Is a carboxy-lyase activity
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Synonyms
  • "5-pyrophosphomevalonate decarboxylase activity" RELATED[ EC:4 ]
    "ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)" RELATED[ EC:4 ]
    "ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)" RELATED[ EC:4 ]
    "mevalonate 5-diphosphate decarboxylase activity" RELATED[ EC:4 ]
    "mevalonate diphosphate decarboxylase activity" RELATED[ EC:4 ]
    "mevalonate pyrophosphate decarboxylase activity" RELATED[ EC:4 ]
    "mevalonate-5-pyrophosphate decarboxylase activity" RELATED[ EC:4 ]
    "pyrophosphomevalonate decarboxylase activity" RELATED[ EC:4 ]
    "pyrophosphomevalonic acid decarboxylase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.1.1.33
KEGG_REACTION:R01121
MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN
Reactome:R-HSA-191414 "MVD decarboxylates MVA5PP to IPPP"
RHEA:23732