FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term aminopeptidase activity ID (Ontology) GO:0004177 (Gene Ontology)
Definition Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.[ EC:3 PubMed:24157837 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       7
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 aminopeptidase activity (all annotations which use CV term, excluding "NOT" statements)       7
     enables | aminopeptidase activity       7
Spanning Tree (Parents/Children)
Only view relationship: 
  peptidase activity
   |__exopeptidase activity
       |__aminopeptidase activity  33 rec.
           |__alanyl aminopeptidase activity
           |__cysteine-type aminopeptidase activity 4 rec.
           |__glutamyl aminopeptidase activity
           |__initiator methionyl aminopeptidase activity 1 rec.
           |__metalloaminopeptidase activity 26 rec.
           |__serine-type aminopeptidase activity 1 rec.
           |__tripeptide aminopeptidase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a exopeptidase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
EC:3.4.11.-
EC:3.4.11.1
EC:3.4.11.21
EC:3.4.11.22
EC:3.4.11.5
EC:3.4.11.6
EC:3.4.11.9
https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE
MetaCyc:3.4.11.21-RXN
MetaCyc:3.4.11.5-RXN
MetaCyc:3.4.11.6-RXN
MetaCyc:3.4.11.9-RXN
MetaCyc:RXN0-5052
Reactome:R-HSA-1236954 "Trimming of peptides by IRAP in endocytic vesicles"
Reactome:R-HSA-2534096 "METAP1/2 demethylates GNAT1"
Reactome:R-HSA-983162 "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases"