FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term serine-type carboxypeptidase activity ID (Ontology) GO:0004185 (Gene Ontology)
Definition Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Also Known As"serine carboxypeptidase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 serine-type carboxypeptidase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | serine-type carboxypeptidase activity       --
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serine-type peptidase activity
 |__serine-type exopeptidase activity__
exopeptidase activity                  |
 |__carboxypeptidase activity__________|
 |__serine-type exopeptidase activity__|
                                       serine-type carboxypeptidase activity  6 rec.
                                        |__peptidoglycan L,D-transpeptidase activity
                                        |__serine-type D-Ala-D-Ala carboxypeptidase activity
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Is a carboxypeptidase activity
serine-type exopeptidase activity
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Synonyms
  • "serine carboxypeptidase activity" EXACT
Secondary IDs
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EC:3.4.16.-
EC:3.4.16.2
EC:3.4.16.5
EC:3.4.16.6
MetaCyc:3.4.16.2-RXN
MetaCyc:3.4.16.5-RXN
Reactome:R-HSA-158251 "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer"