FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term threonine-type endopeptidase activity ID (Ontology) GO:0004298 (Gene Ontology)
Definition Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
Also Known As "threonine endopeptidase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 threonine-type endopeptidase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | threonine-type endopeptidase activity       --
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peptidase activity
 |__endopeptidase activity_____________
 |__threonine-type peptidase activity__|
                                       threonine-type endopeptidase activity  16 rec.
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Is a endopeptidase activity
threonine-type peptidase activity
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Synonyms
  • "26S protease" RELATED[ EC:3 ]
    "alkaline protease" RELATED[ EC:3 ]
    "ingensin" RELATED[ EC:3 ]
    "large multicatalytic protease" NARROW[ EC:3 ]
    "lens neutral proteinase" NARROW[ EC:3 ]
    "MCP" RELATED[ EC:3 ]
    "multicatalytic endopeptidase complex" RELATED[ EC:3 ]
    "multicatalytic proteinase" NARROW[ EC:3 ]
    "multicatalytic proteinase (complex)" NARROW[ EC:3 ]
    "prosome" RELATED[ EC:3 ]
    "proteasome endopeptidase complex" NARROW[ EC:3 ]
    "threonine endopeptidase activity" EXACT
    "tricorn protease" NARROW[ EC:3 ]
    "tricorn proteinase" NARROW[ EC:3 ]
Secondary IDs
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EC:3.4.25.-
Reactome:R-HSA-9818574 "TASP1 cleaves KMT2A"
Reactome:R-HSA-9818577 "TASP1 cleaves KMT2B"