FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term fatty acid synthase activity ID (Ontology) GO:0004312 (Gene Ontology)
Definition Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.[ EC:2 ]
Also Known As "fatty-acid synthase activity"
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Gene Groups Genes
 fatty acid synthase activity (all annotations which use CV term, excluding "NOT" statements)       1      3
     enables | fatty acid synthase activity       --       3
Spanning Tree (Parents/Children)
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  acyltransferase activity
   |__acyltransferase activity, transferring groups other than amino-acyl groups
       |__fatty acid synthase activity  4 rec.
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Is a acyltransferase activity, transferring groups other than amino-acyl groups
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Synonyms
  • "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)" RELATED[ EC:2 ]
    "fatty-acid synthase activity" EXACT
Secondary IDs
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EC:2.3.1.85
MetaCyc:FATTY-ACID-SYNTHASE-RXN
Reactome:R-HSA-163756 "Formation of fatty acid synthase (FAS) dimer"
Reactome:R-HSA-75872 "Conversion of malonyl-CoA and acetyl-CoA to palmitate"
RHEA:14993