FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity ID (Ontology) GO:0004316 (Gene Ontology)
Definition Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.
Also Known As"3-oxoacyl-[acyl-carrier protein] reductase activity" ; "3-oxoacyl-ACP reductase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
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  oxidoreductase activity, acting on CH-OH group of donors
   |__oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
       |__3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity  1 rec.
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Is a oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Synonyms
  • "(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity" RELATED[ EC:1 ]
    "3-ketoacyl acyl carrier protein reductase activity" RELATED[ EC:1 ]
    "3-oxoacyl-[acyl-carrier protein] reductase activity" EXACT
    "3-oxoacyl-ACP reductase activity" EXACT
    "3-oxoacyl-ACPreductase activity" RELATED[ EC:1 ]
    "3-oxoacyl-acyl-carrier-protein reductase activity" RELATED[ EC:1 ]
    "beta-ketoacyl acyl carrier protein (ACP) reductase activity" RELATED[ EC:1 ]
    "beta-ketoacyl reductase activity" RELATED[ EC:1 ]
    "beta-ketoacyl thioester reductase activity" RELATED[ EC:1 ]
    "beta-ketoacyl-ACP reductase activity" RELATED[ EC:1 ]
    "beta-ketoacyl-acyl carrier protein reductase activity" RELATED[ EC:1 ]
    "beta-ketoacyl-acyl-carrier protein(ACP) reductase activity" RELATED[ EC:1 ]
    "NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.100
MetaCyc:3-OXOACYL-ACP-REDUCT-RXN
MetaCyc:RXN-10659
MetaCyc:RXN-11476
MetaCyc:RXN-11480
Reactome:R-HSA-8862152 "2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP"
RHEA:17397