FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term glutamate decarboxylase activity ID (Ontology) GO:0004351 (Gene Ontology)
Definition Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.[ EC:4 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 glutamate decarboxylase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | glutamate decarboxylase activity
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  carbon-carbon lyase activity
   |__carboxy-lyase activity
       |__glutamate decarboxylase activity  2 rec.
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Is a carboxy-lyase activity
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Synonyms
  • "aspartic alpha-decarboxylase" BROAD[ EC:4 ]
    "cysteic acid decarboxylase activity" RELATED[ EC:4 ]
    "gamma-glutamate decarboxylase activity" RELATED[ EC:4 ]
    "L-aspartate-alpha-decarboxylase activity" RELATED[ EC:4 ]
    "L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)" RELATED[ EC:4 ]
    "L-glutamate 1-carboxy-lyase activity" RELATED[ EC:4 ]
    "L-glutamate alpha-decarboxylase activity" RELATED[ EC:4 ]
    "L-glutamic acid decarboxylase activity" RELATED[ EC:4 ]
    "L-glutamic decarboxylase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.1.1.15
MetaCyc:GLUTDECARBOX-RXN
Reactome:R-HSA-888572 "PXLP-K405-GAD1 decarboxylates L-Glu to form GABA"
Reactome:R-HSA-888577 "Synthesis of GABA by GAD2"
RHEA:17785