FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term glutathione transferase activity ID (Ontology) GO:0004364 (Gene Ontology)
Definition Catalysis of the reaction: RX + glutathione = an S-substituted glutathione + a halide anion + H+.
Also Known As "glutathione conjugation reaction"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      38
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 glutathione transferase activity (all annotations which use CV term, excluding "NOT" statements)       3     38
     enables | glutathione transferase activity       --      38
 NOT | enables | glutathione transferase activity       --       2
Spanning Tree (Parents/Children)
Only view relationship: 
  transferase activity
   |__transferase activity, transferring alkyl or aryl (other than methyl) groups
       |__glutathione transferase activity  41 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a transferase activity, transferring alkyl or aryl (other than methyl) groups
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "glutathione conjugation reaction" EXACT
    "glutathione S-alkyl transferase activity" RELATED[ EC:2 ]
    "glutathione S-alkyltransferase activity" RELATED[ EC:2 ]
    "glutathione S-aralkyltransferase activity" RELATED[ EC:2 ]
    "glutathione S-aryltransferase activity" RELATED[ EC:2 ]
    "glutathione S-transferase activity" RELATED[ EC:2 ]
    "RX:glutathione R-transferase activity" RELATED[ EC:2 ]
    "S-(hydroxyalkyl)glutathione lyase activity" RELATED[ EC:2 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:2.5.1.18
MetaCyc:GSHTRAN-RXN
Reactome:R-HSA-176054 "GST dimers conjugate GSH with cytosolic substrates"
Reactome:R-HSA-176059 "GST trimers transfer GS from GSH to luminal substrates"
Reactome:R-HSA-3301943 "GSTK1 dimer transfers GS from GSH to CDNB"
Reactome:R-HSA-5423653 "MGST trimers transfer GS from GSH to AFXBO and AFNBO"
Reactome:R-HSA-9011595 "GSTZ1 dimer dehalogenates DCA"
Reactome:R-HSA-9026777 "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1"
Reactome:R-HSA-9026780 "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1"
Reactome:R-HSA-9026901 "GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1"
Reactome:R-HSA-9026911 "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1"
Reactome:R-HSA-9748996 "GST dimers cleave AZA to 6MP"
Reactome:R-HSA-9753280 "GSTs transfer GSH to NAPQI to form APAP-SG"
RHEA:16437