FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ID (Ontology) GO:0004365 (Gene Ontology)
Definition Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.[ EC:1 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity       --
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  oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
   |__glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity
       |__glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity  4 rec.
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Is a glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity
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Synonyms
  • "3-phosphoglyceraldehyde dehydrogenase activity" RELATED[ EC:1 ]
    "D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)" RELATED[ EC:1 ]
    "dehydrogenase, glyceraldehyde phosphate" RELATED[ EC:1 ]
    "GAPDH activity" RELATED[ EC:1 ]
    "glyceraldehyde phosphate dehydrogenase (NAD)" RELATED[ EC:1 ]
    "glyceraldehyde-3-P-dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-dependent glyceraldehyde phosphate dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity" RELATED[ EC:1 ]
    "NADH-glyceraldehyde phosphate dehydrogenase activity" RELATED[ EC:1 ]
    "phosphoglyceraldehyde dehydrogenase activity" RELATED[ EC:1 ]
    "triosephosphate dehydrogenase activity" BROAD[ EC:1 ]
Secondary IDs
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EC:1.2.1.12
MetaCyc:GAPOXNPHOSPHN-RXN
Reactome:R-HSA-70449 "GADPH tetramer dehydrogenates GA3P"
Reactome:R-HSA-70482 "GAPDH tetramers reduce 1,3BPG to GA3P"
RHEA:10300