FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity ID (Ontology) GO:0004378 (Gene Ontology)
Definition Catalysis of the reaction: a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H+.
Also Known As"GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
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mannosyltransferase activity
 |__alpha-1,3-mannosyltransferase activity_________
 |__GlcNAc(2)-PP-Dol mannosyltransferase activity__|
                                                   GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity  1 rec.
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Is a alpha-1,3-mannosyltransferase activity
GlcNAc(2)-PP-Dol mannosyltransferase activity
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Synonyms
  • "GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity" EXACT systematic_synonym[ EC:2 ]
    "GDP-mannose-oligosaccharide-lipid mannosyltransferase II" RELATED[ EC:2 ]
    "GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity" RELATED[ EC:2 ]
    "glycolipid 3-alpha-mannosyltransferase activity" RELATED[ EC:2 ]
    "guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity" RELATED[ EC:2 ]
    "mannosyltransferase II activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.132
MetaCyc:RXN-5462
RHEA:29515