FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term guanylate cyclase activity ID (Ontology) GO:0004383 (Gene Ontology)
Definition Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.[ EC:4 ]
Also Known As "guanylyl cyclase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
Genes (FBgn)  GO_MOLECULAR_FUNCTION      13
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 guanylate cyclase activity (all annotations which use CV term, excluding "NOT" statements)       4     13
     enables | guanylate cyclase activity       --      13
Spanning Tree (Parents/Children)
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catalytic activity
 |__cyclase activity__________________
lyase activity                        |
 |__phosphorus-oxygen lyase activity__|
                                      guanylate cyclase activity  17 rec.
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Is a cyclase activity
phosphorus-oxygen lyase activity
Part of
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Synonyms
  • "GTP diphosphate-lyase (cyclizing) activity" RELATED[ EC:4 ]
    "GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity" RELATED[ EC:4 ]
    "guanyl cyclase activity" RELATED[ EC:4 ]
    "guanylyl cyclase activity" EXACT
    "receptor guanylate cyclase activity" NARROW
Secondary IDs
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EC:4.6.1.2
MetaCyc:GUANYLCYC-RXN
Reactome:R-HSA-392152 "Soluble guanylate cyclase converts GTP to cGMP"
Reactome:R-HSA-74885 "GUCYs converts GTP to cGMP"
RHEA:13665