FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term heparan sulfate 2-sulfotransferase activity ID (Ontology) GO:0004394 (Gene Ontology)
Definition Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.[ PubMed:9153262 ]
Also Known As"heparan sulfate 2-O-sulfotransferase activity" ; "heparan-sulfate 2-O-sulphotransferase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 heparan sulfate 2-sulfotransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | heparan sulfate 2-sulfotransferase activity
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  proteoglycan sulfotransferase activity
   |__heparan sulfate sulfotransferase activity
       |__heparan sulfate 2-sulfotransferase activity  1 rec.
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Is a heparan sulfate sulfotransferase activity
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Synonyms
  • "heparan sulfate 2-O-sulfotransferase activity" EXACT
    "heparan-sulfate 2-O-sulphotransferase activity" EXACT
    "heparin 2-sulfotransferase activity" RELATED
    "heparin-sulphate 2-sulphotransferase activity" RELATED
Secondary IDs
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MetaCyc:RXN-11558
Reactome:R-HSA-2076508 "HS2ST1 trimer sulfates IdoA at C2 in heparan sulfate"