FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term histone acetyltransferase activity ID (Ontology) GO:0004402 (Gene Ontology)
Definition Catalysis of the reaction: L-lysyl-[histone] + acetyl-CoA = N6-acetyl-L-lysyl-[histone] + CoA + H+.[ PubMed:19056256 ]
Also Known As "histone acetylase activity" ; "histone lysine acetyltransferase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 histone acetyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | histone acetyltransferase activity       --
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Vocabulary search: maintenance 
protein N-acetyltransferase activity
 |__protein-lysine-acetyltransferase activity__
catalytic activity, acting on a protein        |
 |__histone modifying activity_________________|
                                               histone acetyltransferase activity  21 rec.
                                                |__histone H1 acetyltransferase activity
                                                |   |__histone H1-4K34 acetyltransferase activity
                                                |   |__histone H1K75 acetyltransferase activity
                                                |__histone H2A acetyltransferase activity 2 rec.
                                                |   |__histone H2AK5 acetyltransferase activity
                                                |   |__histone H2AK9 acetyltransferase activity
                                                |__histone H2B acetyltransferase activity
                                                |   |__histone H2BK5 acetyltransferase activity
                                                |   |__histone H2BK12 acetyltransferase activity
                                                |__histone H3 acetyltransferase activity 6 rec.
                                                |   |__histone H3K4 acetyltransferase activity
                                                |   |__histone H3K9 acetyltransferase activity
                                                |   |__histone H3K14 acetyltransferase activity 1 rec.
                                                |   |__histone H3K18 acetyltransferase activity 1 rec.
                                                |   |__histone H3K23 acetyltransferase activity 2 rec.
                                                |   |__histone H3K27 acetyltransferase activity 1 rec.
                                                |   |__histone H3K36 acetyltransferase activity
                                                |   |__histone H3K56 acetyltransferase activity
                                                |   |__histone H3K122 acetyltransferase activity
                                                |__histone H4 acetyltransferase activity 10 rec.
                                                    |__histone H4K5 acetyltransferase activity
                                                    |__histone H4K8 acetyltransferase activity
                                                    |__histone H4K12 acetyltransferase activity
                                                    |__histone H4K16 acetyltransferase activity 3 rec.
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Is a protein-lysine-acetyltransferase activity
histone modifying activity
Part of
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Synonyms
  • "acetyl-CoA:histone acetyltransferase activity" RELATED
    "H2A/H2B histone acetyltransferase activity" NARROW
    "H3/H4 histone acetyltransferase activity" NARROW
    "H4/H2 histone acetyltransferase activity" NARROW
    "H4/H2A acetyltransferase activity" NARROW
    "histone acetokinase activity" RELATED
    "histone acetylase activity" EXACT
    "histone lysine acetyltransferase activity" EXACT
    "histone transacetylase activity" RELATED
    "nucleosome-histone acetyltransferase activity" RELATED
Secondary IDs
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MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN
Reactome:R-HSA-3301237 "KAT2 complexes acetylate histone H3"
Reactome:R-HSA-3301345 "Elongator complex acetylates replicative histone H3, H4"
Reactome:R-HSA-3318413 "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3"
Reactome:R-HSA-3318415 "ATF2 acetylates histone H2B, H4"
Reactome:R-HSA-3318486 "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3"
Reactome:R-HSA-3321805 "NSL acetylates histone H4"
Reactome:R-HSA-3321883 "MSL acetylates histone H4"
Reactome:R-HSA-3321975 "NuA4 complex acetylates histone H2A, HIST1H4"
Reactome:R-HSA-3451147 "KAT5 HAT complex acetylates TCF4 gene at histone H4"
Reactome:R-HSA-3662318 "Type B histone acetlytransferase complex acetylates histone H4"
Reactome:R-HSA-3662335 "EP300 acetylates histone H2A, H2B, H3, H4"
Reactome:R-HSA-3697008 "CREBBP acetylates histone H2B, H3, H4"
Reactome:R-HSA-3697920 "CLOCK acetylates lysine-10 of histone H3, H4"
Reactome:R-HSA-5144542 "CLOCK acetylates lysine-15 of histone H3, H4"
Reactome:R-HSA-5250938 "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9"
Reactome:R-HSA-9926482 "CREBBP, EP300 acetylate MITF-M"
RHEA:21992