FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term histone acetyltransferase activity ID (Ontology) GO:0004402 (Gene Ontology)
Definition Catalysis of the reaction: L-lysyl-[histone] + acetyl-CoA = N6-acetyl-L-lysyl-[histone] + CoA + H+.[ PubMed:19056256 ]
Also Known As "histone acetylase activity" ; "histone lysine acetyltransferase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      11
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 histone acetyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       8     11
     enables | histone acetyltransferase activity       --      11
Spanning Tree (Parents/Children)
Only view relationship: 
protein N-acetyltransferase activity
 |__protein-lysine-acetyltransferase activity__
catalytic activity, acting on a protein        |
 |__histone modifying activity_________________|
                                               histone acetyltransferase activity  21 rec.
                                                |__histone H1 acetyltransferase activity
                                                |   |__histone H1-4K34 acetyltransferase activity
                                                |   |__histone H1K75 acetyltransferase activity
                                                |__histone H2A acetyltransferase activity 2 rec.
                                                |   |__histone H2AK5 acetyltransferase activity
                                                |   |__histone H2AK9 acetyltransferase activity
                                                |__histone H2B acetyltransferase activity
                                                |   |__histone H2BK5 acetyltransferase activity
                                                |   |__histone H2BK12 acetyltransferase activity
                                                |__histone H3 acetyltransferase activity 6 rec.
                                                |   |__histone H3K4 acetyltransferase activity
                                                |   |__histone H3K9 acetyltransferase activity
                                                |   |__histone H3K14 acetyltransferase activity 1 rec.
                                                |   |__histone H3K18 acetyltransferase activity 1 rec.
                                                |   |__histone H3K23 acetyltransferase activity 2 rec.
                                                |   |__histone H3K27 acetyltransferase activity 1 rec.
                                                |   |__histone H3K36 acetyltransferase activity
                                                |   |__histone H3K56 acetyltransferase activity
                                                |   |__histone H3K122 acetyltransferase activity
                                                |__histone H4 acetyltransferase activity 10 rec.
                                                    |__histone H4K5 acetyltransferase activity
                                                    |__histone H4K8 acetyltransferase activity
                                                    |__histone H4K12 acetyltransferase activity
                                                    |__histone H4K16 acetyltransferase activity 3 rec.
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Is a protein-lysine-acetyltransferase activity
histone modifying activity
Part of
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Synonyms
  • "acetyl-CoA:histone acetyltransferase activity" RELATED
    "H2A/H2B histone acetyltransferase activity" NARROW
    "H3/H4 histone acetyltransferase activity" NARROW
    "H4/H2 histone acetyltransferase activity" NARROW
    "H4/H2A acetyltransferase activity" NARROW
    "histone acetokinase activity" RELATED
    "histone acetylase activity" EXACT
    "histone lysine acetyltransferase activity" EXACT
    "histone transacetylase activity" RELATED
    "nucleosome-histone acetyltransferase activity" RELATED
Secondary IDs
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MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN
Reactome:R-HSA-3301237 "KAT2 complexes acetylate histone H3"
Reactome:R-HSA-3301345 "Elongator complex acetylates replicative histone H3, H4"
Reactome:R-HSA-3318413 "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3"
Reactome:R-HSA-3318415 "ATF2 acetylates histone H2B, H4"
Reactome:R-HSA-3318486 "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3"
Reactome:R-HSA-3321805 "NSL acetylates histone H4"
Reactome:R-HSA-3321883 "MSL acetylates histone H4"
Reactome:R-HSA-3321975 "NuA4 complex acetylates histone H2A, HIST1H4"
Reactome:R-HSA-3451147 "KAT5 HAT complex acetylates TCF4 gene at histone H4"
Reactome:R-HSA-3662318 "Type B histone acetlytransferase complex acetylates histone H4"
Reactome:R-HSA-3662335 "EP300 acetylates histone H2A, H2B, H3, H4"
Reactome:R-HSA-3697008 "CREBBP acetylates histone H2B, H3, H4"
Reactome:R-HSA-3697920 "CLOCK acetylates lysine-10 of histone H3, H4"
Reactome:R-HSA-5144542 "CLOCK acetylates lysine-15 of histone H3, H4"
Reactome:R-HSA-5250938 "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9"
RHEA:21992