FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term holocytochrome-c synthase activity ID (Ontology) GO:0004408 (Gene Ontology)
Definition Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.[ EC:4 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 holocytochrome-c synthase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | holocytochrome-c synthase activity
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catalytic activity
 |__catalytic activity, acting on a protein__
lyase activity                               |
 |__carbon-sulfur lyase activity_____________|
                                             holocytochrome-c synthase activity  1 rec.
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Is a carbon-sulfur lyase activity
catalytic activity, acting on a protein
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Synonyms
  • "cytochrome c heme-lyase activity" RELATED[ EC:4 ]
    "cytochrome c synthase activity" RELATED[ EC:4 ]
    "holocytochrome c synthetase activity" RELATED[ EC:4 ]
    "holocytochrome-c apocytochrome-c-lyase (heme-forming)" RELATED[ EC:4 ]
    "holocytochrome-c apocytochrome-c-lyase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.4.1.17
MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN
Reactome:R-HSA-9866217 "HCCS inserts heme into cytochrome c"
RHEA:22648