FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term homogentisate 1,2-dioxygenase activity ID (Ontology) GO:0004411 (Gene Ontology)
Definition Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate + H+.[ EC:1 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 homogentisate 1,2-dioxygenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | homogentisate 1,2-dioxygenase activity       1
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oxidoreductase activity, acting on single donors with incorporation of molecular oxygen__
dioxygenase activity_____________________________________________________________________|
                                                                                         oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
                                                                                          |__homogentisate 1,2-dioxygenase activity  1 rec.
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Is a oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
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Synonyms
  • "homogentisate dioxygenase activity" RELATED[ EC:1 ]
    "homogentisate oxidase activity" RELATED[ EC:1 ]
    "homogentisate oxygenase activity" RELATED[ EC:1 ]
    "homogentisate:oxygen 1,2-oxidoreductase (decyclizing)" RELATED[ EC:1 ]
    "homogentisic acid oxidase activity" RELATED[ EC:1 ]
    "homogentisic acid oxygenase activity" RELATED[ EC:1 ]
    "homogentisic oxygenase activity" RELATED[ EC:1 ]
    "homogentisicase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.13.11.5
KEGG_REACTION:R02519
MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN
Reactome:R-HSA-71164 "HGD dioxygenates homogentisate"
RHEA:15449
UM-BBD_reactionID:r0105