FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term hydroxyacylglutathione hydrolase activity ID (Ontology) GO:0004416 (Gene Ontology)
Definition Catalysis of the reaction: an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H+.
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 hydroxyacylglutathione hydrolase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | hydroxyacylglutathione hydrolase activity       1
Spanning Tree (Parents/Children)
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  hydrolase activity, acting on ester bonds
   |__thiolester hydrolase activity
       |__hydroxyacylglutathione hydrolase activity  1 rec.
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Is a thiolester hydrolase activity
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Synonyms
  • "acetoacetylglutathione hydrolase activity" RELATED[ EC:3 ]
    "glyoxalase II activity" RELATED[ EC:3 ]
    "S-(2-hydroxyacyl)glutathione hydrolase activity" RELATED[ EC:3 ]
    "S-2-hydroxylacylglutathione hydrolase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.1.2.6
MetaCyc:RXN-7919
Reactome:R-HSA-6783221 "HAGH hydrolyses (R)-S-LGSH to GSH and LACT"
RHEA:21864
RHEA:25245