FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phosphatidylinositol-3-phosphate phosphatase activity ID (Ontology) GO:0004438 (Gene Ontology)
Definition Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.[ EC:3 ]
Also Known As "phosphatidylinositol-3-phosphatase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphatidylinositol-3-phosphate phosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphatidylinositol-3-phosphate phosphatase activity
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  phosphatidylinositol phosphate phosphatase activity
   |__phosphatidylinositol monophosphate phosphatase activity
       |__phosphatidylinositol-3-phosphate phosphatase activity  6 rec.
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Is a phosphatidylinositol monophosphate phosphatase activity
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Synonyms
  • "1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity" RELATED[ EC:3 ]
    "D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity" RELATED[ EC:3 ]
    "inositol 1,3-bisphosphate phosphatase activity" RELATED[ EC:3 ]
    "inositol-1,3-bisphosphate 3-phosphatase activity" RELATED[ EC:3 ]
    "inositol-polyphosphate 3-phosphatase activity" RELATED[ EC:3 ]
    "phosphatidyl-3-phosphate 3-phosphohydrolase activity" RELATED[ EC:3 ]
    "phosphatidylinositol-3-phosphatase activity" EXACT
Secondary IDs
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EC:3.1.3.64
MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN
Reactome:R-HSA-1675795 "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane"
Reactome:R-HSA-1675994 "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane"
Reactome:R-HSA-1676114 "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane"
Reactome:R-HSA-1676141 "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane"
Reactome:R-HSA-6809325 "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane"
Reactome:R-HSA-6809720 "PI3P is dephosphorylated to PI by MTM1:MTMR12"
Reactome:R-HSA-6809777 "PI3P is dephosphorylated to PI by MTMR2:SBF1"
Reactome:R-HSA-6809975 "PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane"
RHEA:12316
RHEA:42328