FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term isocitrate dehydrogenase (NAD+) activity ID (Ontology) GO:0004449 (Gene Ontology)
Definition Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.
Also Known As "isocitrate dehydrogenase (NAD) activity" ; "isocitrate:NAD+ oxidoreductase (decarboxylating)" ; "NAD dependent isocitrate dehydrogenase activity" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 isocitrate dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)       1      3
     enables | isocitrate dehydrogenase (NAD+) activity       --       3
Spanning Tree (Parents/Children)
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  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
   |__isocitrate dehydrogenase [NAD(P)+] activity
       |__isocitrate dehydrogenase (NAD+) activity  4 rec.
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Is a isocitrate dehydrogenase [NAD(P)+] activity
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Synonyms
  • "isocitrate dehydrogenase (NAD) activity" EXACT[ EC:1 ]
    "isocitrate:NAD+ oxidoreductase (decarboxylating)" EXACT[ EC:1 ]
    "NAD dependent isocitrate dehydrogenase activity" EXACT[ EC:1 ]
    "NAD isocitrate dehydrogenase activity" EXACT[ EC:1 ]
    "NAD isocitric dehydrogenase activity" EXACT[ EC:1 ]
    "NAD-linked isocitrate dehydrogenase activity" EXACT[ EC:1 ]
    "NAD-specific isocitrate dehydrogenase activity" EXACT[ EC:1 ]
    "nicotinamide adenine dinucleotide isocitrate dehydrogenase activity" EXACT[ EC:1 ]
Secondary IDs
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EC:1.1.1.41
Reactome:R-HSA-70967 "IDH3 complex decarboxylates isocitrate"
RHEA:23632