FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term L-lactate dehydrogenase (NAD+) activity ID (Ontology) GO:0004459 (Gene Ontology)
Definition Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 L-lactate dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)       2
     enables | L-lactate dehydrogenase (NAD+) activity       2
Spanning Tree (Parents/Children)
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lactate dehydrogenase activity
 |__L-lactate dehydrogenase activity___________________________________________________
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor  |
 |__L-2-hydroxycarboxylate dehydrogenase (NAD+) activity_______________________________|
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Is a L-2-hydroxycarboxylate dehydrogenase (NAD+) activity
L-lactate dehydrogenase activity
Part of
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Synonyms
  • "L-lactate dehydrogenase activity" BROAD
    "L-lactic acid dehydrogenase activity" RELATED[ EC:1 ]
    "L-lactic dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.27
MetaCyc:L-LACTATE-DEHYDROGENASE-RXN
Reactome:R-HSA-6807826 "LDHAL6B reduces PYR to LACT"
Reactome:R-HSA-70510 "LDH tetramer oxidises LACT to PYR"
Reactome:R-HSA-71849 "LDH tetramer reduces PYR to LACT"
RHEA:23444