FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term leukotriene-A4 hydrolase activity ID (Ontology) GO:0004463 (Gene Ontology)
Definition Catalysis of the reaction: H2O + leukotriene A(4) = leukotriene B(4).[ EC:3 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 leukotriene-A4 hydrolase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | leukotriene-A4 hydrolase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  hydrolase activity, acting on ether bonds
   |__ether hydrolase activity
       |__leukotriene-A4 hydrolase activity  1 rec.
           |__isochorismatase activity
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Is a ether hydrolase activity
Part of
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Synonyms
  • "(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity" RELATED[ EC:3 ]
    "leukotriene A(4) hydrolase activity" RELATED[ EC:3 ]
    "leukotriene A4 hydrolase activity" RELATED[ EC:3 ]
    "LTA-4 hydrolase activity" RELATED[ EC:3 ]
    "LTA4 hydrolase activity" RELATED[ EC:3 ]
    "LTA4H" RELATED[ EC:3 ]
Secondary IDs
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EC:3.3.2.6
KEGG_REACTION:R03057
MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN
Reactome:R-HSA-266072 "LTA4 is hydolysed to LTB4 by LTA4H"
RHEA:22324