FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term mannose-6-phosphate isomerase activity ID (Ontology) GO:0004476 (Gene Ontology)
Definition Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 mannose-6-phosphate isomerase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | mannose-6-phosphate isomerase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  intramolecular oxidoreductase activity
   |__intramolecular oxidoreductase activity, interconverting aldoses and ketoses
       |__mannose-6-phosphate isomerase activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "D-mannose-6-phosphate aldose-ketose-isomerase activity" RELATED[ EC:5 ]
    "D-mannose-6-phosphate ketol-isomerase activity" RELATED[ EC:5 ]
    "mannose phosphate isomerase activity" RELATED[ EC:5 ]
    "phosphohexoisomerase activity" BROAD[ EC:5 ]
    "phosphohexomutase activity" BROAD[ EC:5 ]
    "phosphomannoisomerase activity" RELATED[ EC:5 ]
    "phosphomannose isomerase activity" RELATED[ EC:5 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:5.3.1.8
MetaCyc:MANNPISOM-RXN
Reactome:R-HSA-3781832 "Defective MPI does not isomerize Fru6P to Man6P"
Reactome:R-HSA-532549 "MPI isomerises Fru6P to Man6P"
RHEA:12356