FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term methionyl-tRNA formyltransferase activity ID (Ontology) GO:0004479 (Gene Ontology)
Definition Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.[ EC:2 ]
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       1
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
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 Genes
 methionyl-tRNA formyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | methionyl-tRNA formyltransferase activity       1
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transferase activity, transferring one-carbon groups
 |__hydroxymethyl-, formyl- and related transferase activity__
catalytic activity, acting on RNA                             |
 |__catalytic activity, acting on a tRNA______________________|
                                                              methionyl-tRNA formyltransferase activity  1 rec.
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Is a hydroxymethyl-, formyl- and related transferase activity
catalytic activity, acting on a tRNA
Part of
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Synonyms
  • "10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity" RELATED[ EC:2 ]
    "conversion of met-tRNAf to fmet-tRNA" RELATED
    "conversion of mitochondrial met-tRNAf to fmet-tRNA" RELATED
    "formylmethionyl-transfer ribonucleic synthetase activity" RELATED[ EC:2 ]
    "methionyl ribonucleic formyltransferase activity" RELATED[ EC:2 ]
    "methionyl-transfer ribonucleate methyltransferase activity" RELATED[ EC:2 ]
    "methionyl-transfer ribonucleic transformylase activity" RELATED[ EC:2 ]
    "methionyl-transfer RNA transformylase activity" RELATED[ EC:2 ]
    "methionyl-tRNA Met formyltransferase activity" RELATED[ EC:2 ]
    "methionyl-tRNA transformylase activity" RELATED[ EC:2 ]
    "mitochondrial N-terminal peptidyl-methionine N-formylation" RELATED
    "N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity" RELATED[ EC:2 ]
    "N-terminal peptidyl-methionine N-formylation" RELATED
    "N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.1.2.9
MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN
Reactome:R-HSA-5389841 "MTFMT formylates methionyl-tRNA"
RHEA:24380