FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term monooxygenase activity ID (Ontology) GO:0004497 (Gene Ontology)
Definition Catalysis of the incorporation of one atom of molecular oxygen (O2) into the substrate and the reduction of the other atom of O2 to water.[ PubMed:1444267 ]
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      97
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 monooxygenase activity (all annotations which use CV term, excluding "NOT" statements)       7     97
     enables | monooxygenase activity       --      97
 NOT | enables | monooxygenase activity       --       2
Spanning Tree (Parents/Children)
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  catalytic activity
   |__oxidoreductase activity
       |__monooxygenase activity  121 rec.
           |__2-hydroxypyridine 5-monooxygenase activity
           |__3-demethoxyubiquinol 3-hydroxylase activity
           |__3-hydroxybenzoate 2-monooxygenase activity
           |__4-methoxybenzoate monooxygenase (O-demethylating) activity
           |__20-aldehyde-leukotriene B4 20-monooxygenase activity
           |__20-hydroxy-leukotriene B4 omega oxidase activity
           |__acyl-lipid omega-(9-4) desaturase activity
           |__all-trans retinoic acid 18-hydroxylase activity
           |__ammonia monooxygenase activity
           |__arachidonate monooxygenase activity
           |   |__arachidonate epoxygenase activity(+)
           |__beta-carotene 3-hydroxylase activity
           |__catechol oxidase activity 6 rec.
           |__coumarin 7-hydroxylase activity
           |__deoxyhypusine monooxygenase activity 1 rec.
           |__eupatolide synthase activity
           |__fatty acid in-chain hydroxylase activity
           |__ferulate 5-hydroxylase activity
           |__gamma-glutamyl hercynylcysteine sulfoxide synthase activity
           |__inositol oxygenase activity 1 rec.
           |__jasmonoyl-isoleucine-12-hydroxylase activity
           |__kynurenine 7,8-hydroxylase activity
           |__limonene monooxygenase activity
           |   |__(R)-limonene 6-monooxygenase activity
           |   |__(S)-limonene 3-monooxygenase activity
           |   |__(S)-limonene 6-monooxygenase activity
           |   |__(S)-limonene 7-monooxygenase activity
           |   |__limonene 1,2-monooxygenase [NAD(P)H) activity
           |__linoleic acid epoxygenase activity
           |__luciferin monooxygenase activity
           |   |__Cypridina-luciferin 2-monooxygenase activity
           |   |__Latia-luciferin monooxygenase (demethylating) activity
           |   |__Oplophorus-luciferin 2-monooxygenase activity
           |   |__Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
           |   |__Renilla-luciferin 2-monooxygenase activity
           |   |__Watasenia-luciferin 2-monooxygenase activity
           |__ornithine N5-monooxygenase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen 5 rec.
           |   |__4alpha-monomethylsterol monooxygenase activity
           |   |__C-4 methylsterol oxidase activity
           |   |__cholesterol 26-hydroxylase activity
           |   |__CMP-N-acetylneuraminate monooxygenase activity
           |   |__fatty acid 2-hydroxylase activity(+) 1 rec.
           |   |__phosphatidylcholine 12-monooxygenase activity
           |   |__sphingolipid C4-monooxygenase activity
           |   |__tyrosinase activity 4 rec.
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 7 rec.
           |   |__(+)-taxifolin 5'-hydroxylase activity
           |   |__(-)-menthol monooxygenase activity
           |   |__(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity
           |   |__(5alpha)-campestan-3-one hydroxylase activity
           |   |__1-deoxy-11-oxopentalenate oxygenase activity
           |   |__1-hydroxy-2-naphthoate hydroxylase activity
           |   |__2,2',3-trihydroxybiphenyl monooxygenase activity
           |   |__2,4-dichlorophenol 6-monooxygenase activity
           |   |__2,6-dihydroxypyridine 3-monooxygenase activity
           |   |__2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity
           |   |__2-hydroxybiphenyl 3-monooxygenase (NADH) activity
           |   |__2-hydroxycyclohexanone 2-monooxygenase activity
           |   |__2-hydroxyquinoline 8-monooxygenase activity
           |   |__2-isopropylphenol monooxygenase activity
           |   |__2-nitrophenol 2-monooxygenase activity
           |   |__2-octaprenyl-6-methoxyphenol hydroxylase activity
           |   |__2-polyprenylphenol 6-hydroxylase activity
           |   |__2-propylphenol monooxygenase activity
           |   |__3-(3-hydroxyphenyl)propionate hydroxylase activity
           |   |__3-demethoxyubiquinone 3-hydroxylase (NADH) activity 1 rec.
           |   |__3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase [NAD(P)H] activity
           |   |__3-hydroxybenzoate 4-monooxygenase activity
           |   |__3-hydroxybenzoate 6-monooxygenase activity
           |   |__3-hydroxyphenylacetate 6-hydroxylase activity
           |   |__4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity
           |   |__4-aminobenzoate 1-monooxygenase activity
           |   |__4-hydroxyacetophenone monooxygenase activity
           |   |__4-hydroxybenzoate 1-hydroxylase activity
           |   |__4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity(+)
           |   |__4-hydroxybenzoate 3-monooxygenase activity
           |   |__4-hydroxyphenylacetate 1-monooxygenase activity
           |   |__4-hydroxyquinoline 3-monooxygenase activity
           |   |__4-nitrocatechol 4-monooxygenase activity
           |   |__4-nitrophenol 2-monooxygenase activity
           |   |__4-nitrophenol 4-monooxygenase activity
           |   |__4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity
           |   |__4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity
           |   |__5-methylphenazine-1-carboxylate 1-monooxygenase (NADH) activity
           |   |__5-pyridoxate dioxygenase activity
           |   |__6-hydroxynicotinate 3-monooxygenase activity
           |   |__6-oxocineole dehydrogenase activity
           |   |__albendazole monooxygenase activity
           |   |__alkene monooxygenase activity
           |   |__alpha-pinene monooxygenase (NADH) activity
           |   |__anandamide epoxidase activity(+)
           |   |__anhydrotetracycline monooxygenase activity
           |   |__anthranilate 3-monooxygenase (deaminating) activity
           |   |__anthraniloyl-CoA monooxygenase activity
           |   |__apigenin-7,4'-dimethyl ether 6-hydroxylase activity
           |   |__benzoyl-CoA 3-monooxygenase activity
           |   |__chlorophyllide a oxygenase activity
           |   |__cyclohexanone monooxygenase activity
           |   |__cyclopentanone monooxygenase activity
           |   |__dimethyl sulfide monooxygenase activity
           |   |__dimethylsulfoxide oxygenase activity
           |   |__F-actin monooxygenase activity 1 rec.
           |   |__FAD-dependent urate hydroxylase activity
           |   |__fluorescent chlorophyll catabolite monooxygenase (deformylase) activity
           |   |__genkwanin 6-hydroxylase activity
           |   |__hydroxyphenylacetonitrile 2-monooxygenase activity
           |   |__hypotaurine monooxygenase activity 2 rec.
           |   |__imidazoleacetate 4-monooxygenase activity
           |   |__indole-3-pyruvate monooxygenase activity
           |   |__ketosteroid monooxygenase activity
           |   |__kynurenine 3-monooxygenase activity 1 rec.
           |   |__L-lysine 6-monooxygenase (NADPH) activity
           |   |__leukotriene-E4 20-monooxygenase activity
           |   |__limonene 1,2-monooxygenase [NAD(P)H) activity
           |   |__magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity
           |   |__melilotate 3-monooxygenase activity
           |   |__methane monooxygenase [NAD(P)H] activity
           |   |__methanesulfonate monooxygenase activity
           |   |__N,N-dimethylaniline monooxygenase activity 2 rec.
           |   |__nitric-oxide synthase activity 1 rec.
           |   |__oleate 12-hydroxylase activity
           |   |__orcinol 2-monooxygenase activity
           |   |__pentachlorophenol monooxygenase activity
           |   |__phenol 2-monooxygenase activity
           |   |__phenylacetone monooxygenase activity
           |   |__phenylacetyl-CoA 1,2-epoxidase activity
           |   |__precorrin-3B synthase activity
           |   |__pyrrole-2-carboxylate monooxygenase (NADH) activity
           |   |__questin monooxygenase (NADPH) activity
           |   |__sakuranetin 6-hydroxylase activity
           |   |__salicylate 1-monooxygenase activity
           |   |__salicylate 5-hydroxylase (NADH) activity
           |   |__senecionine N-oxygenase activity
           |   |__syn-pimaradiene 6beta-hydroxylase activity
           |   |__taxifolin 8-monooxygenase activity
           |   |__taxoid 14-beta-hydroxylase activity
           |   |__toluene 2-monooxygenase activity
           |   |__toluene 4-monooxygenase activity
           |   |__toluene-sulfonate methyl-monooxygenase activity
           |   |__trans-cinnamate 2-monooxygenase activity
           |   |__tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity(+)
           |   |__tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity(+)
           |   |__trimethylamine monooxygenase activity
           |   |__trimethyluric acid monooxygenase activity
           |   |__vanillate monooxygenase activity
           |   |__zeaxanthin 2-beta-hydroxylase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen 5 rec.
           |   |__1-aminocyclopropane-1-carboxylate oxidase activity
           |   |__dopamine beta-monooxygenase activity 3 rec.
           |   |__peptidylglycine monooxygenase activity 1 rec.
           |   |__tyramine-beta hydroxylase activity 3 rec.
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 5 rec.
           |   |__(+)-abscisic acid 8'-hydroxylase activity
           |   |__(+)-menthofuran synthase activity
           |   |__(R)-limonene 6-monooxygenase activity
           |   |__(S)-limonene 3-monooxygenase activity
           |   |__(S)-limonene 6-monooxygenase activity
           |   |__(S)-limonene 7-monooxygenase activity
           |   |__1,8-cineole 2-exo-monooxygenase activity
           |   |__2,5-diketocamphane 1,2-monooxygenase activity
           |   |__2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity
           |   |__2-hydroxyisoflavanone synthase activity
           |   |__3,5 dichloro-THPH synthase activity
           |   |__3,9-dihydroxypterocarpan 6a-monooxygenase activity
           |   |__3-chloro THPH synthase activity
           |   |__3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity
           |   |__3-hydroxyindolin-2-one monooxygenase activity
           |   |__3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity
           |   |__3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity
           |   |__4'-methoxyisoflavone 2'-hydroxylase activity
           |   |__4-hydroxyphenylacetaldehyde oxime monooxygenase activity
           |   |__4-hydroxyphenylacetate 3-monooxygenase activity
           |   |__5-epi-aristolochene-1,3-dihydroxylase activity
           |   |__5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity
           |   |__7-deoxyloganate 7-hydroxylase activity
           |   |__7-deoxyloganin 7-hydroxylase activity
           |   |__9beta-pimara-7,15-diene oxidase activity
           |   |__11-oxo-beta-amyrin 30-oxidase activity
           |   |__22alpha-hydroxysteroid 23-monooxygenase activity
           |   |__24S-hydroxycholesterol 7-alpha-hydroxylase activity
           |   |__25-hydroxycholesterol 7-alpha-hydroxylase activity
           |   |__abieta-7,13-dien-18-ol hydroxylase activity
           |   |__abieta-7,13-diene hydroxylase activity
           |   |__aflatoxin B synthase activity
           |   |__alkanal monooxygenase (FMN-linked) activity
           |   |__alkanesulfonate monooxygenase activity
           |   |__alpha-humulene 10-hydroxylase activity
           |   |__alpha-tocopherol omega-hydroxylase activity
           |   |__angelicin synthase activity
           |   |__arachidonate omega-hydroxylase activity
           |   |__aromatase activity
           |   |__benzoate 4-monooxygenase activity
           |   |__beta-amyrin 11-oxidase activity
           |   |__beta-amyrin 16beta-monooxygenase activity
           |   |__beta-amyrin 28-monooxygenase activity
           |   |__brassinolide synthase activity
           |   |__carotene epsilon hydroxylase activity
           |   |__cholesterol 7-alpha-monooxygenase activity
           |   |__cholesterol 24-hydroxylase activity
           |   |__costunolide 3beta-hydroxylase activity
           |   |__costunolide synthase activity
           |   |__cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity
           |   |__dammarenediol 12-hydroxylase activity
           |   |__deoxysarpagine hydroxylase activity
           |   |__dibenzothiophene monooxygenase activity
           |   |__dibenzothiophene sulfone monooxygenase (NADH) activity
           |   |__dihydrochelirubine 12-monooxygenase activity
           |   |__dihydrosanguinarine 10-monooxygenase activity
           |   |__DMNT synthase activity
           |   |__ecdysteroid 25-hydroxylase activity 1 rec.
           |   |__ent-cassa-12,15-diene 11-hydroxylase activity
           |   |__ent-isokaurene C2-hydroxylase activity
           |   |__ent-kaurene oxidase activity
           |   |__ent-kaurenoic acid monooxygenase activity
           |   |__estrogen 2-hydroxylase activity
           |   |__estrogen 16-alpha-hydroxylase activity
           |   |__farnesoate epoxidase activity 1 rec.
           |   |__fatty acid omega-1 hydroxylase activity(+) 1 rec.
           |   |__fatty acid omega-hydroxylase activity(+)
           |   |__flavanone 2-hydroxylase activity
           |   |__flavonoid 3',5'-hydroxylase activity
           |   |__flavonoid 3'-monooxygenase activity
           |   |__fraxetin 5-hydroxylase activity
           |   |__geraniol 10-hydroxylase activity
           |   |__germacrene A acid 8beta-hydroxylase activity
           |   |__germacrene A hydroxylase activity
           |   |__glyceollin synthase activity
           |   |__heme oxygenase (decyclizing) activity 1 rec.
           |   |__homomethionine N-monooxygenase activity
           |   |__indole-2-monooxygenase activity
           |   |__indole-3-carbonyl nitrile 4-hydroxylase activity
           |   |__indolin-2-one monooxygenase activity
           |   |__isoflavone 2'-hydroxylase activity
           |   |__isoflavone 3'-hydroxylase activity
           |   |__isoleucine N-monooxygenase (oxime forming) activity
           |   |__L-phenylalanine N-monooxygenase activity
           |   |__labd-13Z-ene-9,15,16-triol synthase activity
           |   |__leukotriene-B4 20-monooxygenase activity
           |   |__linalool 8-monooxygenase activity
           |   |__lithocholate 6beta-hydroxylase activity
           |   |__methyl farnesoate epoxidase activity 1 rec.
           |   |__methyltetrahydroprotoberberine 14-monooxygenase activity
           |   |__N-methylcoclaurine 3'-monooxygenase activity
           |   |__naringenin 2-hydroxylase activity
           |   |__nitrilotriacetate monooxygenase activity
           |   |__parthenolide 3beta-hydroxylase activity
           |   |__parthenolide synthase activity
           |   |__phenylacetate 2-hydroxylase activity
           |   |__pipecolic acid N-hydroxylase activity
           |   |__protopanaxadiol 6-hydroxylase activity
           |   |__protopine 6-monooxygenase activity
           |   |__psoralen synthase (NADPH) activity
           |   |__quinine 3-monooxygenase activity
           |   |__squalene monooxygenase activity
           |   |__steroid 17-alpha-monooxygenase activity(+)
           |   |__steroid 21-monooxygenase activity(+)
           |   |__steroid 22S-hydroxylase activity
           |   |__sterol 12-alpha-hydroxylase activity
           |   |__sterol 14-demethylase activity
           |   |__tabersonine 16-hydroxylase activity
           |   |__taurochenodeoxycholate 6alpha-hydroxylase activity
           |   |__taxane 10-beta-hydroxylase activity
           |   |__taxane 13-alpha-hydroxylase activity
           |   |__taxoid 2alpha-hydroxylase activity
           |   |__taxoid 7beta-hydroxylase activity
           |   |__testosterone 16-alpha-hydroxylase activity
           |   |__thalianol hydroxylase activity
           |   |__trans-cinnamate 4-monooxygenase activity
           |   |__tryptophan N-monooxygenase activity
           |   |__tyrosine N-monooxygenase activity
           |   |__valine N-monooxygenase (oxime forming) activity
           |   |__vinorine hydroxylase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 4 rec.
           |   |__2-methoxy-6-polyprenolphenol 4-hydroxylase activity 1 rec.
           |   |__3-ketosteroid 9-alpha-monooxygenase activity
           |   |__4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity 1 rec.
           |   |__alkane 1-monooxygenase activity 1 rec.
           |   |__butane monooxygenase activity
           |   |__calcidiol 1-monooxygenase activity
           |   |__camphor 5-monooxygenase activity
           |   |__cholest-4-en-3-one 26-monooxygenase activity
           |   |__cholestanetetraol 26-dehydrogenase activity
           |   |__cholesterol monooxygenase (side-chain-cleaving) activity
           |   |__choline monooxygenase activity
           |   |__corticosterone 18-monooxygenase activity
           |   |__ecdysteroid 2-hydroxylase activity 1 rec.
           |   |__ecdysteroid 22-hydroxylase activity 1 rec.
           |   |__midchain alkane hydroxylase activity
           |   |__p-cymene methyl hydroxylase activity
           |   |__pheophorbide a oxygenase activity
           |   |__spheroidene monooxygenase activity
           |   |__steroid 11-beta-monooxygenase activity
           |   |__zeaxanthin epoxidase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen 4 rec.
           |   |__glyceryl-ether monooxygenase activity
           |   |__mandelate 4-monooxygenase activity
           |   |__phenylalanine 4-monooxygenase activity 2 rec.
           |   |__tryptophan 5-monooxygenase activity 2 rec.
           |   |__tyrosine 3-monooxygenase activity 1 rec.
           |__oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
           |   |__1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity
           |   |__2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity
           |   |__arginine 2-monooxygenase activity
           |   |__Cypridina-luciferin 2-monooxygenase activity
           |   |__L-lysine 2-monooxygenase activity
           |   |__lactate 2-monooxygenase activity
           |   |__nitronate monooxygenase (FMN-linked) activity
           |   |__nitronate monooxygenase activity
           |   |__Oplophorus-luciferin 2-monooxygenase activity
           |   |__phenylalanine 2-monooxygenase activity
           |   |__Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
           |   |__Renilla-luciferin 2-monooxygenase activity
           |   |__tryptophan 2-monooxygenase activity
           |   |__Watasenia-luciferin 2-monooxygenase activity
           |__p-coumarate 3-hydroxylase activity
           |__phylloquinone monooxygenase (2,3-epoxidizing) activity
           |__retinoic acid 4-hydroxylase activity
           |   |__all-trans retinoic acid 4-hydrolase activity
           |__secalciferol 1-monooxygenase activity
           |__steroid hydroxylase activity 6 rec.
           |   |__cholesterol 25-hydroxylase activity
           |   |__cholesterol 26-hydroxylase activity
           |   |__cholesterol monooxygenase (side-chain-cleaving) activity
           |   |__ecdysone 20-monooxygenase activity 1 rec.
           |   |__ecdysteroid 2-hydroxylase activity 1 rec.
           |   |__ecdysteroid 22-hydroxylase activity 1 rec.
           |   |__ecdysteroid 25-hydroxylase activity 1 rec.
           |   |__estradiol 6-beta-monooxygenase activity
           |   |__estrogen 2-hydroxylase activity
           |   |__estrogen 16-alpha-hydroxylase activity
           |   |__progesterone monooxygenase activity(+)
           |   |__steroid 7-alpha-hydroxylase activity(+)
           |   |__steroid 9-alpha-monooxygenase activity
           |   |__steroid 11-beta-monooxygenase activity
           |   |__steroid 15-alpha-hydroxylase activity
           |   |__steroid 17-alpha-monooxygenase activity(+)
           |   |__steroid 21-monooxygenase activity(+)
           |   |__steroid 22S-hydroxylase activity
           |   |__sterol 12-alpha-hydroxylase activity
           |   |__testosterone 6-beta-hydroxylase activity
           |   |__testosterone 16-alpha-hydroxylase activity
           |   |__testosterone 16-beta-hydroxylase activity
           |   |__vitamin D 23-hydroxylase activity(+)
           |   |__vitamin D 24-hydroxylase activity(+) 1 rec.
           |   |__vitamin D 25-hydroxylase activity
           |__taxadiene 5-alpha-hydroxylase activity
           |__thiophene-2-carbonyl-CoA monooxygenase activity
           |__tryptamine 4-monooxygenase activity
           |__typhasterol C-23 hydroxylase activity
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Synonyms
  • "hydroxylase activity" RELATED
    "mixed-function oxidase" RELATED
Secondary IDs
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Reactome:R-HSA-143468 "MEOS oxidizes ethanol to acetaldehyde"
Reactome:R-HSA-156526 "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO"
Reactome:R-HSA-211882 "CYP3A7 can 6beta-hydroxylate testosterone"
Reactome:R-HSA-211904 "CYP4F12 18-hydroxylates ARA"
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Reactome:R-HSA-211919 "CYP4F8 19-hydroxylates PGH2"
Reactome:R-HSA-211924 "CYP4B1 12-hydroxylates ARA"
Reactome:R-HSA-211929 "CYP2C19 5-hydroxylates omeprazole"
Reactome:R-HSA-211948 "CYP3A4 can N-demethylate loperamide"
Reactome:R-HSA-211959 "CYP3A43 6b-hydroxylates TEST"
Reactome:R-HSA-211960 "CYP2U1 19-hydroxylates ARA"
Reactome:R-HSA-211962 "CYP4F11 16-hydroxylates 3OH-PALM"
Reactome:R-HSA-211968 "CYP2W1 oxidises INDOL"
Reactome:R-HSA-211988 "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation"
Reactome:R-HSA-211991 "Cyclophosphamide is 4-hydroxylated by CYP2B6"
Reactome:R-HSA-212004 "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation"
Reactome:R-HSA-212005 "CYP2F1 dehydrogenates 3-methylindole"
Reactome:R-HSA-213175 "CYP3A4,5 oxidise AFB1 to AFXBO"
Reactome:R-HSA-215526 "CYP4F3 20-hydroxylates LTB4"
Reactome:R-HSA-2161795 "Arachidonate is hydroxylated to 16-HETE by CYP(1)"
Reactome:R-HSA-2161814 "Arachidonate is hydroxylated to 19-HETE by CYP(2)"
Reactome:R-HSA-2161890 "Arachidonate is epoxidated to 5,6-EET by CYP(4)"
Reactome:R-HSA-2161899 "Arachidonate is epoxidated to 8,9-EET by CYP(5)"
Reactome:R-HSA-2161940 "Arachidonate is hydroxylated to 20-HETE by CYP(3)"
Reactome:R-HSA-2162191 "Unknown enzyme hydroxylates DMPhOH"
Reactome:R-HSA-217258 "FMO2:FAD:Mg2+ S-oxidises MTZ"
Reactome:R-HSA-5423647 "CYP2A13 oxidises AFM1 to AFM1E"
Reactome:R-HSA-5423664 "CYP3A4,5 hydroxylates AFB1 to AFQ1"
Reactome:R-HSA-5423672 "CYP1A2, 3A4 oxidise AFB1 to AFNBO"
Reactome:R-HSA-5423678 "CYP1A2 hydroxylates AFB1 to AFM1"
Reactome:R-HSA-5602242 "Defective CYP2U1 does not omega-hydroxylate ARA"
Reactome:R-HSA-5602272 "Defective CYP4F22 does not 20-hydroxylate TrXA3"
Reactome:R-HSA-5602295 "CYP4F22 20-hydroxylates TrXA3"
Reactome:R-HSA-5605147 "Defective CYP1B1 does not 4-hydroxylate EST17b"
Reactome:R-HSA-76354 "Vinyl chloride is oxidized to 2-Chloroethylene oxide"
Reactome:R-HSA-76373 "N-hydroxylation of 4-aminobiphenyl"
Reactome:R-HSA-76386 "CYP1A2 S-demethylates 6MMP"
Reactome:R-HSA-76397 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI)"
Reactome:R-HSA-76416 "Benzene is hydroxylated to phenol"
Reactome:R-HSA-76426 "N-atom dealkylation of caffeine"
Reactome:R-HSA-76434 "Dehalogenation of carbon tetrachloride to form a free radical"
Reactome:R-HSA-76456 "O-atom dealkylation of dextromethorphan"
Reactome:R-HSA-76466 "CYP4A11 omega-hydroxylates DDCX"
Reactome:R-HSA-76472 "Ethylene is oxidized to Ethylene oxide by CYP1A1"
Reactome:R-HSA-76475 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide"
Reactome:R-HSA-8865107 "MICAL1 produces NADP+, H2O2"
Reactome:R-HSA-9018874 "CYP monooxygenates EPA to 18(S)-HpEPE"
Reactome:R-HSA-9027042 "CPY4 -oxidises 14(S)-HDHA to MaR-L1"
Reactome:R-HSA-9027043 "CYPs hydroxylate DHA to 14(R)-HDHA"
Reactome:R-HSA-9027044 "CYP4 -oxidises 14(R)-HDHA to MaR-L2"
Reactome:R-HSA-9027302 "CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA"
Reactome:R-HSA-9027321 "CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA"
Reactome:R-HSA-9037761 "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1"
Reactome:R-HSA-9749986 "CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA"
Reactome:R-HSA-9750016 "CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA"
Reactome:R-HSA-9753285 "CYP2E1 monooxygenates APAP to NAPQI"
Reactome:R-HSA-9756138 "CYP3A4 monooxygenates ATVL to 2-OH-ATVL"
Reactome:R-HSA-9756162 "CYP3A4 monooxygenates ATV to 4-OH-ATV"
Reactome:R-HSA-9756169 "CYP3A4 monooxygenates ATV to 2-OH-ATV"
Reactome:R-HSA-9756180 "CYP3A4 monooxygenates ATVL to 4-OH-ATVL"
Reactome:R-HSA-9915971 "Arachidonate is epoxidated to 11,12-EET by CYP(5)"
Reactome:R-HSA-9915992 "Arachidonate is hydroxylated to 17-HETE by CYP(1)"
Reactome:R-HSA-9915993 "Arachidonate is hydroxylated to 18-HETE by CYP(1)"
Reactome:R-HSA-9915997 "Arachidonate is epoxidated to 14,15-EET by CYP(5)"
Reactome:R-HSA-9971246 "Unknown CYP 450 omega-hydroxylates C10 fatty acid"