FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term kynurenine 3-monooxygenase activity ID (Ontology) GO:0004502 (Gene Ontology)
Definition Catalysis of the reaction: L-kynurenine + H+ + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP+.[ EC:1 ]
Also Known As"kynurenine 3-hydroxylase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 kynurenine 3-monooxygenase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | kynurenine 3-monooxygenase activity
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monooxygenase activity_________________________________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen__|
                                                                                         oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
                                                                                          |__kynurenine 3-monooxygenase activity  1 rec.
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Is a oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
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Synonyms
  • "kynurenine 3-hydroxylase activity" EXACT
    "kynurenine hydroxylase activity" RELATED[ EC:1 ]
    "L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)" RELATED[ EC:1 ]
    "L-kynurenine-3-hydroxylase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.14.13.9
KEGG_REACTION:R01960
MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN
Reactome:R-HSA-71200 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O"
RHEA:20545