FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term tyrosine 3-monooxygenase activity ID (Ontology) GO:0004511 (Gene Ontology)
Definition Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.[ EC:1 ]
Also Known As "tyrosine 3-hydroxylase activity" ; "tyrosine hydroxylase activity"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 tyrosine 3-monooxygenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | tyrosine 3-monooxygenase activity       1
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monooxygenase activity_________________________________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen__|
                                                                                         oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
                                                                                          |__tyrosine 3-monooxygenase activity  1 rec.
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Is a oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
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Synonyms
  • "L-tyrosine hydroxylase activity" RELATED[ EC:1 ]
    "L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" RELATED[ EC:1 ]
    "tyrosine 3-hydroxylase activity" EXACT
    "tyrosine hydroxylase activity" EXACT
Secondary IDs
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EC:1.14.16.2
MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN
Reactome:R-HSA-209823 "Tyrosine is hydroxylated to dopa"
RHEA:18201