FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term nicotinate phosphoribosyltransferase activity ID (Ontology) GO:0004516 (Gene Ontology)
Definition Catalysis of the reaction: nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.[ PubMed:7503993 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 nicotinate phosphoribosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | nicotinate phosphoribosyltransferase activity
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  ligase activity
   |__ligase activity, forming carbon-nitrogen bonds
       |__nicotinate phosphoribosyltransferase activity  1 rec.
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Is a ligase activity, forming carbon-nitrogen bonds
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Synonyms
  • "niacin ribonucleotidase activity" RELATED[ EC:6 ]
    "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" RELATED[ EC:6 ]
    "nicotinic acid mononucleotide glycohydrolase activity" RELATED[ EC:6 ]
    "nicotinic acid mononucleotide pyrophosphorylase activity" RELATED[ EC:6 ]
    "nicotinic acid phosphoribosyltransferase activity" RELATED[ EC:6 ]
Secondary IDs
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EC:6.3.4.21
KEGG_REACTION:R01724
MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN
Reactome:R-HSA-197186 "NAPRT1 dimer transfers PRIB to NCA to form NAMN"
RHEA:36163