FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

nuclease activity

ID (Ontology)

GO:0004518 (Gene Ontology)

Definition

Catalysis of the cleavage of ester linkages within nucleic acids.[ ISBN:0198547684 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
nuclease activity (all annotations which use CV term, excluding "NOT" statements)
enables \| nuclease activity	--
NOT \| enables \| nuclease activity	--

Spanning Tree (Parents/Children)

  catalytic activity
   |__catalytic activity, acting on a nucleic acid
       |__nuclease activity  155 rec.
           |__DNA nuclease activity 70 rec.
           |   |__DNA endonuclease activity(+) 49 rec.
           |   |__DNA exonuclease activity(+) 24 rec.
           |__endonuclease activity 101 rec.
           |   |__DNA endonuclease activity(+) 49 rec.
           |   |__RNA endonuclease activity(+) 69 rec.
           |__exonuclease activity 57 rec.
           |   |__3'-5' exonuclease activity(+) 42 rec.
           |   |__5'-3' exonuclease activity(+) 13 rec.
           |   |__DNA exonuclease activity(+) 24 rec.
           |   |__phosphodiesterase I activity
           |   |__RNA exonuclease activity(+) 27 rec.
           |__RNA nuclease activity 95 rec.
               |__double-stranded RNA-specific ribonuclease activity(+) 4 rec.
               |__RNA endonuclease activity(+) 69 rec.
               |__RNA exonuclease activity(+) 27 rec.
               |__tRNA-specific ribonuclease activity(+) 10 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	catalytic activity, acting on a nucleic acid
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts