FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ribonuclease P activity ID (Ontology) GO:0004526 (Gene Ontology)
Definition Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.[ EC:3 ]
Also Known As"RNase P" ; "tRNA 5' leader endonuclease activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 ribonuclease P activity (all annotations which use CV term, excluding "NOT" statements)
     contributes_to | ribonuclease P activity       --
     enables | ribonuclease P activity       --
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RNA endonuclease activity
 |__RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism__
RNA nuclease activity                                                               |
 |__tRNA-specific ribonuclease activity_____________________________________________|
hydrolase activity, acting on ester bonds                                           |
 |__RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism__|
catalytic activity, acting on a tRNA                                                |
 |__tRNA-specific ribonuclease activity_____________________________________________|
                                                                                    ribonuclease P activity  6 rec.
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Is a tRNA-specific ribonuclease activity
RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
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Synonyms
  • "RNase P" EXACT
    "tRNA 5' leader endonuclease activity" EXACT
Secondary IDs
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EC:3.1.26.5
MetaCyc:3.1.26.5-RXN
Reactome:R-HSA-5696810 "RNase P cleaves the 5' end of pre-tRNA"
Wikipedia:RNase_P