FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

exonuclease activity

ID (Ontology)

GO:0004527 (Gene Ontology)

Definition

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.[ ISBN:0198547684 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
exonuclease activity (all annotations which use CV term, excluding "NOT" statements)
enables \| exonuclease activity
NOT \| enables \| exonuclease activity

Spanning Tree (Parents/Children)

hydrolase activity
 |__hydrolase activity, acting on ester bonds__
catalytic activity, acting on a nucleic acid   |
 |__nuclease activity__________________________|
                                               exonuclease activity  57 rec.
                                                |__3'-5' exonuclease activity 42 rec.
                                                |   |__3'-5'-DNA exonuclease activity(+) 18 rec.
                                                |   |__3'-5'-RNA exonuclease activity(+) 21 rec.
                                                |__5'-3' exonuclease activity 13 rec.
                                                |   |__5'-3' DNA exonuclease activity(+) 6 rec.
                                                |   |__5'-3' RNA exonuclease activity 5 rec.
                                                |__DNA exonuclease activity 24 rec.
                                                |   |__DNA exonuclease activity, producing 5'-phosphomonoesters(+) 23 rec.
                                                |__phosphodiesterase I activity
                                                |__RNA exonuclease activity 27 rec.
                                                    |__5'-hydroxyl dinucleotide hydrolase activity
                                                    |__RNA exonuclease activity, producing 5'-phosphomonoesters(+) 26 rec.

Spanning Tree View Settings
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Relationships
Is a	nuclease activity hydrolase activity, acting on ester bonds
Part of
Synonyms & Secondary IDs
Synonyms
	"exonuclease IX activity" NARROW
Secondary IDs

External Crossreferences & Linkouts