FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term 5'-3' RNA exonuclease activity ID (Ontology) GO:0004534 (Gene Ontology)
Definition Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.[ ISBN:0198547684 ]
Also Known As "5'-3' exoribonuclease activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 5'-3' RNA exonuclease activity (all annotations which use CV term, excluding "NOT" statements)       1      3
     enables | 5'-3' RNA exonuclease activity       --       3
Spanning Tree (Parents/Children)
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exonuclease activity
 |__5'-3' exonuclease activity________________________________
RNA exonuclease activity                                      |
 |__RNA exonuclease activity, producing 5'-phosphomonoesters__|
                                                              5'-3' RNA exonuclease activity  4 rec.
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Is a 5'-3' exonuclease activity
RNA exonuclease activity, producing 5'-phosphomonoesters
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Synonyms
  • "5'-3' exoribonuclease activity" EXACT
Secondary IDs
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Reactome:R-HSA-429845 "5' to 3' exoribonuclease hydrolyzes decapped mRNA"
Reactome:R-HSA-6791227 "47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA"
Reactome:R-HSA-9915442 "EXOG cleaves RNA dinucleotide from nascent mitochondrial DNA"
Reactome:R-HSA-9935265 "DXO hydrolyzes uncapped RNA"
Reactome:R-HSA-9935299 "XRN2 5'-3' exonucleolytically hydrolyzes uncapped RNA"
Reactome:R-HSA-9946917 "XRN1 incompletely hydrolyzes DENV decapped mRNA"
Reactome:R-HSA-9971054 "XRN2 degrades downstream RNA fragment, promoting transcription termination"