FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term nucleoside diphosphate kinase activity ID (Ontology) GO:0004550 (Gene Ontology)
Definition Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.[ EC:2 ]
Also Known As"nucleoside-diphosphate kinase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 nucleoside diphosphate kinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | nucleoside diphosphate kinase activity       --
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kinase activity
 |__nucleobase-containing compound kinase activity_______________
transferase activity, transferring phosphorus-containing groups  |
 |__phosphotransferase activity, phosphate group as acceptor_____|
                                                                 nucleoside diphosphate kinase activity  4 rec.
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Is a phosphotransferase activity, phosphate group as acceptor
nucleobase-containing compound kinase activity
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Synonyms
  • "ATP:nucleoside-diphosphate phosphotransferase activity" RELATED[ EC:2 ]
    "NDK activity" RELATED[ EC:2 ]
    "nucleoside 5'-diphosphate kinase activity" RELATED[ EC:2 ]
    "nucleoside 5'-diphosphate phosphotransferase activity" RELATED[ EC:2 ]
    "nucleoside diphosphate (UDP) kinase activity" RELATED[ EC:2 ]
    "nucleoside diphosphokinase activity" RELATED[ EC:2 ]
    "nucleoside-diphosphate kinase activity" EXACT
    "nucleotide phosphate kinase activity" RELATED[ EC:2 ]
    "UDP kinase activity" RELATED[ EC:2 ]
    "uridine diphosphate kinase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.7.4.6
MetaCyc:NUCLEOSIDE-DIP-KIN-RXN
Reactome:R-HSA-2162096 "carbovir diphosphate + ATP => carbovir triphosphate + ADP"
Reactome:R-HSA-482619 "(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)"
Reactome:R-HSA-482621 "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)"
Reactome:R-HSA-482804 "(d)NDP + ATP <=> (d)NTP + ADP (NME4)"
Reactome:R-HSA-482812 "(d)NTP + ADP <=> (d)NDP + ATP (NME4)"
Reactome:R-HSA-6806877 "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs"
Reactome:R-HSA-9748969 "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP"
Reactome:R-HSA-9748999 "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP"
Reactome:R-HSA-9755013 "NME1,2 hexamers phosphorylate RBV-DP"