FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term alpha-1,4-glucosidase activity ID (Ontology) GO:0004558 (Gene Ontology)
Definition Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.[ EC:3 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 alpha-1,4-glucosidase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | alpha-1,4-glucosidase activity
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  glucosidase activity
   |__alpha-glucosidase activity
       |__alpha-1,4-glucosidase activity  10 rec.
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Is a alpha-glucosidase activity
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Synonyms
  • "acid maltase activity" RELATED[ EC:3 ]
    "alpha-D-glucosidase activity" RELATED[ EC:3 ]
    "alpha-D-glucoside glucohydrolase activity" RELATED[ EC:3 ]
    "alpha-glucopyranosidase activity" RELATED[ EC:3 ]
    "alpha-glucoside hydrolase activity" RELATED[ EC:3 ]
    "glucoinvertase activity" RELATED[ EC:3 ]
    "glucosidoinvertase activity" RELATED[ EC:3 ]
    "glucosidosucrase activity" RELATED[ EC:3 ]
    "lysosomal alpha-glucosidase activity" BROAD[ EC:3 ]
    "maltase-glucoamylase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.2.1.20
MetaCyc:MALTODEXGLUCOSID-RXN
Reactome:R-HSA-189053 "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose"
Reactome:R-HSA-189102 "maltose + H2O => 2 D-glucose (maltase-glucoamylase)"
Reactome:R-HSA-191101 "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)"
Reactome:R-HSA-191108 "maltose + H2O => 2 D-glucose (sucrase-isomaltase)"
Reactome:R-HSA-191116 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)"
Reactome:R-HSA-5659861 "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)"
Reactome:R-HSA-5659879 "Defective SI does not hydrolyze iMal"
Reactome:R-HSA-5659899 "Defective SI does not hydrolyze maltotriose"
Reactome:R-HSA-5659922 "Defective SI does not hydrolyze Mal"