FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term alpha-mannosidase activity ID (Ontology) GO:0004559 (Gene Ontology)
Definition Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.[ EC:3 ]
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       9
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 alpha-mannosidase activity (all annotations which use CV term, excluding "NOT" statements)       3      9
     enables | alpha-mannosidase activity       --       9
Spanning Tree (Parents/Children)
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  hydrolase activity, hydrolyzing O-glycosyl compounds
   |__mannosidase activity
       |__alpha-mannosidase activity  23 rec.
           |__glycoprotein endo-alpha-1,2-mannosidase activity 2 rec.
           |__mannan 1,2-(1,3)-alpha-mannosidase activity
           |__mannan endo-1,6-alpha-mannosidase activity
           |__mannan exo-1,2-1,6-alpha-mannosidase activity
           |__mannoside alpha-1,4-mannosidase activity
           |__mannosyl-oligosaccharide mannosidase activity 14 rec.
               |__mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 12 rec.
               |__mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity 1 rec.
               |__mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
               |__mannosyl-oligosaccharide 1,6-alpha-mannosidase activity 1 rec.
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Is a mannosidase activity
Part of
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Synonyms
  • "1,2-alpha-D-mannosidase activity" NARROW[ EC:3 ]
    "1,2-alpha-mannosidase" NARROW[ EC:3 ]
    "alpha-D-mannopyranosidase activity" RELATED[ EC:3 ]
    "alpha-D-mannosidase activity" RELATED[ EC:3 ]
    "alpha-D-mannoside mannohydrolase activity" RELATED[ EC:3 ]
    "exo-alpha-mannosidase activity" RELATED[ EC:3 ]
    "p-nitrophenyl-alpha-mannosidase activity" NARROW[ EC:3 ]
Secondary IDs
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EC:3.2.1.24
MetaCyc:3.2.1.24-RXN
Reactome:R-HSA-6799545 "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5"
Reactome:R-HSA-8853686 "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3"
Reactome:R-HSA-9694656 "Spike trimer glycoside chains are extended"